Asymmetric synthesis of β-amino ketones by using cinchona alkaloid-based chiral phase transfer catalysts
Literature Information
Weihua Li, Yifeng Wang, Danqian Xu
A highly enantioselective nucleophilic addition of ketones to imines catalyzed by chiral phase-transfer catalysts (N-quaternised cinchona alkaloid ammonium salts) has been developed, and the process affords the Mannich reaction products with tertiary stereocenters in good to high yields (up to 95%) with excellent enantioselectivities (up to 97% ee).
Related Literature
Cross-linking approaches for block copolymer nano-assemblies via RAFT-mediated polymerization-induced self-assembly
Shenzhen Li, Guang Han
DOI: 10.1039/D0PY00627K
Ring opening polymerization of macrocyclic oligoesters derived from renewable sources
Antxon Martínez de Ilarduya, Sebastián Muñoz Guerra
DOI: 10.1039/D0PY00258E
On the limitations of cationic polymerization of vinyl monomers in aqueous dispersed media
Aurélie Destephen
DOI: 10.1039/D1PY01046H
Development of a fully bio-based hyperbranched benzoxazine
Wanan Cai, Zhicheng Wang, Zhaohui Shu, Wenbin Liu, Jun Wang, Jian Qiu
DOI: 10.1039/D1PY01451J
Green-light photocleavable meso-methyl BODIPY building blocks for macromolecular chemistry
Paul Strasser, Pauline Stadler, Patrick Breiteneder, Günther Redhammer, Markus Himmelsbach, Oliver Brüggemann, Uwe Monkowius, Ian Teasdale
DOI: 10.1039/D1PY01245B
Effect of polymerisation by microwave on the physical properties of molecularly imprinted polymers (MIPs) specific for caffeine
Heli A. Brahmbhatt, Alexander Surtees, Cavan Tierney, Oluwabukunmi A. Ige, Elena V. Piletska, Thomas Swift
DOI: 10.1039/D0PY00921K
Multifunctional system for combined chemodynamic–photodynamic therapy employing the endothelin axis based on conjugated polymer nanoparticles
Khalaf A. Jasim, Ibrahim F. Waheed
DOI: 10.1039/D1PY00964H
Role of thiol oxidation by air in the mechanism of the self-initiated thermal thiol–ene polymerization
DOI: 10.1039/D1PY01301G
You might also like
What is the market or research trend for N-(4-Methoxybenzyl)-2-pyridinamine (CAS: 52818-63-0)?
N-(4-Methoxybenzyl)-2-pyridinamine (CAS: 52818-63-0) is increasingly being used ...
What precautions should be taken when handling Ethyl 4-(2-chlorophenyl)-1,3-thiazole-2-carboxylate (CAS: 1050507-06-6)?
When handling Ethyl 4-(2-chlorophenyl)-1,3-thiazole-2-carboxylate, appropriate p...
What regulatory guidelines apply to diethyldiselane (CAS: 628-39-7)?
Diethyldiselane (CAS: 628-39-7) is classified under the Globally Harmonized Syst...
What is the market or research trend for oxocopper (CAS: 12053-18-8)?
The market for oxocopper (CAS: 12053-18-8) is primarily driven by its use in cat...
What is the market or research trend for 5-{[(2-Methyl-2-propanyl)oxy]carbonyl}-5-azaspiro[2.4]heptane-7-carboxylic acid?
The market for 5-{[(2-Methyl-2-propanyl)oxy]carbonyl}-5-azaspiro[2.4]heptane-7-c...
What is 2-(1-Pyrrolidinyl)-4-pyridinamine (CAS: 35981-63-6)?
2-(1-Pyrrolidinyl)-4-pyridinamine is a chemical compound with the CAS number 359...
What are the physical and chemical properties of 2-(3-Pyridinyl)-1-azabicyclo[2.2.2]octane (CAS: 91556-75-1)?
2-(3-Pyridinyl)-1-azabicyclo[2.2.2]octane (CAS: 91556-75-1) is a crystalline sol...
How is (S)-Alpha-allyl-proline hydrochloride (CAS: 129704-91-2) typically synthesized?
(S)-Alpha-allyl-proline hydrochloride is usually synthesized via a Wittig reacti...
What is 3-Methyl-1,2-oxazole-5-carboxylic acid (CAS: 4857-42-5)?
3-Methyl-1,2-oxazole-5-carboxylic acid (CAS: 4857-42-5) is an organic compound w...
How is Lys-SMCC-DM1 (CAS: 1281816-04-3) typically synthesized?
Lys-SMCC-DM1 is synthesized via a multi-step process involving the coupling of S...
Source Journal
Organic & Biomolecular Chemistry

Organic & Biomolecular Chemistry (OBC) publishes original and high impact research and reviews in organic chemistry. We welcome research that shows new or significantly improved protocols or methodologies in total synthesis, synthetic methodology or physical and theoretical organic chemistry as well as research that shows a significant advance in the organic chemistry or molecular design aspects of chemical biology, catalysis, supramolecular and macromolecular chemistry, theoretical chemistry, mechanism-oriented physical organic chemistry, medicinal chemistry or natural products. Articles published in the journal should report new work which makes a highly-significant impact in the field. Routine and incremental work is generally not suitable for publication in the journal. More details about key areas of our scope are below. In all cases authors should include in their article clear rationale for why their research has been carried out.











![1-(1-Benzyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-benzo[d]imidazol-2(3H)-one structure 1-(1-Benzyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-benzo[d]imidazol-2(3H)-one structure](https://static.chemtradehub.com/structs/603/60373-71-9-7dfb.webp)

![5'-Fluoro-[2,3'-biindolinylidene]-2',3-dione structure 5'-Fluoro-[2,3'-biindolinylidene]-2',3-dione structure](https://static.chemtradehub.com/structs/251/251903-00-1-9cb1.webp)
