Activation of the hypervalent fluoroiodane reagent by hydrogen bonding to hexafluoroisopropanol
Literature Information
Publication Date
2018-09-18
DOI
10.1039/C8OB02236D
Impact Factor
3.876
Authors
Harsimran K. Minhas, William Riley, Alison M. Stuart, Martyna Urbonaite
View Original
Abstract
Hexafluoroisopropan-2-ol (HFIP) is an excellent solvent for promoting fluorinations with the hypervalent fluoroiodane reagent 1 and crucially, it removes the need for transition metals or TREAT-HF activators. The fluoroiodane reagent 1 was used in HFIP to monofluorinate 1,3-ketoesters and to fluorocyclise unsaturated carboxylic acids in excellent yields under mild reaction conditions.
Recommended Journals
Russian Journal of Organic Chemistry
Current Opinion in Solid State & Materials Science
Nature Medicine
Journal of Natural Medicines
Drug Discovery Today
New Journal of Chemistry
Chemical Communications
Russian Journal of Bioorganic Chemistry
Current Opinion in Colloid & Interface Science
Russian Journal of Applied Chemistry
Related Literature
Identifying competitive tin- or metal-free catalyst combinations to tailor polyurethane prepolymer and network properties
Priscilla Arnould, Lionel Bosco, Federico Sanz, Frédéric N. Simon, Stéphane Fouquay, Guillaume Michaud, Jean Raynaud, Vincent Monteil
2020-08-25
Paper
DOI: 10.1039/D0PY00864H
General approach to prepare polymers bearing pendant isocyanate groups
Rodrigo Navarro, Carolina García, Juan Rodríguez-Hernández, Carlos Elvira, Angel Marcos-Fernández, Alberto Gallardo, Helmut Reinecke
2020-07-28
Communication
DOI: 10.1039/D0PY00989J
Multifunctional system for combined chemodynamic–photodynamic therapy employing the endothelin axis based on conjugated polymer nanoparticles
Khalaf A. Jasim, Ibrahim F. Waheed
2021-08-24
Paper
DOI: 10.1039/D1PY00964H
Synthesis of polyethers from epoxides via a binary organocatalyst system
Ge-Ge Gu, Li-Yang Wang, Rong Zhang, Tian-Jun Yue, Bai-Hao Ren, Wei-Min Ren
2021-10-19
Paper
DOI: 10.1039/D1PY01085A
Development of the first panchromatic BODIPY-based one-component iodonium salts for initiating the photopolymerization processes
Monika Topa-Skwarczyńska, Mariusz Galek, Magdalena Jankowska, Fabrice Morlet-Savary, Bernadette Graff, Jacques Lalevée, Roman Popielarz
2021-11-03
Paper
DOI: 10.1039/D1PY01263K
Green-light photocleavable meso-methyl BODIPY building blocks for macromolecular chemistry
Paul Strasser, Pauline Stadler, Patrick Breiteneder, Günther Redhammer, Markus Himmelsbach, Oliver Brüggemann, Uwe Monkowius, Ian Teasdale
2021-11-16
Paper
DOI: 10.1039/D1PY01245B
Balancing the transesterification reactivity of isosorbide with diphenyl carbonate: preferential activation of exo-OH
Ming Zhang, Yifei Tu, Zibo Zhou, Guozhang Wu
2020-07-23
Paper
DOI: 10.1039/D0PY00764A
Tellurophene-containing π-conjugated polymers with unique heteroatom–heteroatom interactions by post-element-transformation of an organotitanium polymer
Hiroki Nishiyama, Feng Zheng, Shinsuke Inagi, Hiroyuki Fueno, Ikuyoshi Tomita
2020-07-07
Communication
DOI: 10.1039/D0PY00724B
You might also like
Compound Q&A
What is the market or research trend for N-(4-Methoxybenzyl)-2-pyridinamine (CAS: 52818-63-0)?
N-(4-Methoxybenzyl)-2-pyridinamine (CAS: 52818-63-0) is increasingly being used ...
52818-63-0N-(4-Methoxybenzyl)-...
Compound Q&A
What precautions should be taken when handling Ethyl 4-(2-chlorophenyl)-1,3-thiazole-2-carboxylate (CAS: 1050507-06-6)?
When handling Ethyl 4-(2-chlorophenyl)-1,3-thiazole-2-carboxylate, appropriate p...
1050507-06-6Ethyl 4-(2-chlorophe...
Compound Q&A
What regulatory guidelines apply to diethyldiselane (CAS: 628-39-7)?
Diethyldiselane (CAS: 628-39-7) is classified under the Globally Harmonized Syst...
628-39-7Diethyldiselane
Compound Q&A
What is the market or research trend for oxocopper (CAS: 12053-18-8)?
The market for oxocopper (CAS: 12053-18-8) is primarily driven by its use in cat...
12053-18-8oxocopper; oxo-(oxoc...
Compound Q&A
What is the market or research trend for 5-{[(2-Methyl-2-propanyl)oxy]carbonyl}-5-azaspiro[2.4]heptane-7-carboxylic acid?
The market for 5-{[(2-Methyl-2-propanyl)oxy]carbonyl}-5-azaspiro[2.4]heptane-7-c...
1268519-54-55-{[(2-Methyl-2-prop...
Compound Q&A
What is 2-(1-Pyrrolidinyl)-4-pyridinamine (CAS: 35981-63-6)?
2-(1-Pyrrolidinyl)-4-pyridinamine is a chemical compound with the CAS number 359...
35981-63-62-(1-Pyrrolidinyl)-4...
Compound Q&A
What are the physical and chemical properties of 2-(3-Pyridinyl)-1-azabicyclo[2.2.2]octane (CAS: 91556-75-1)?
2-(3-Pyridinyl)-1-azabicyclo[2.2.2]octane (CAS: 91556-75-1) is a crystalline sol...
91556-75-12-(3-Pyridinyl)-1-az...
Compound Q&A
How is (S)-Alpha-allyl-proline hydrochloride (CAS: 129704-91-2) typically synthesized?
(S)-Alpha-allyl-proline hydrochloride is usually synthesized via a Wittig reacti...
129704-91-2(S)-Alpha-allyl-prol...
Compound Q&A
What is 3-Methyl-1,2-oxazole-5-carboxylic acid (CAS: 4857-42-5)?
3-Methyl-1,2-oxazole-5-carboxylic acid (CAS: 4857-42-5) is an organic compound w...
4857-42-53-Methyl-1,2-oxazole...
Compound Q&A
How is Lys-SMCC-DM1 (CAS: 1281816-04-3) typically synthesized?
Lys-SMCC-DM1 is synthesized via a multi-step process involving the coupling of S...
1281816-04-3Lys-SMCC-DM1
Source Journal
Organic & Biomolecular Chemistry
CiteScore:
3.4
Self-citation Rate:
10.3%
Articles per Year:
1041
Organic & Biomolecular Chemistry (OBC) publishes original and high impact research and reviews in organic chemistry. We welcome research that shows new or significantly improved protocols or methodologies in total synthesis, synthetic methodology or physical and theoretical organic chemistry as well as research that shows a significant advance in the organic chemistry or molecular design aspects of chemical biology, catalysis, supramolecular and macromolecular chemistry, theoretical chemistry, mechanism-oriented physical organic chemistry, medicinal chemistry or natural products. Articles published in the journal should report new work which makes a highly-significant impact in the field. Routine and incremental work is generally not suitable for publication in the journal. More details about key areas of our scope are below. In all cases authors should include in their article clear rationale for why their research has been carried out.
Recommended Compounds
![(2R,6S)-6-[(Benzyloxy)methyl]-4-{[(2-methyl-2-propanyl)oxy]carbonyl}-2-morpholinecarboxylic acid structure](https://static.chemtradehub.com/structs/109/1093085-91-6-3382.webp "(2R,6S)-6-[(Benzyloxy)methyl]-4-{[(2-methyl-2-propanyl)oxy]carbonyl}-2-morpholinecarboxylic acid structure")
(2R,6S)-6-[(Benzyloxy)methyl]-4-{[(2-methyl-2-propanyl)oxy]carbonyl}-2-morpholinecarboxylic acid
CAS Number:
1093085-91-6
Molecular Formula:
C18H25NO6
![1-[6-(1H-Imidazol-1-yl)-3-pyridinyl]methanamine structure](https://static.chemtradehub.com/structs/914/914637-08-4-8825.webp "1-[6-(1H-Imidazol-1-yl)-3-pyridinyl]methanamine structure")
Recommended Suppliers
Disclaimer
This page provides academic journal information for reference and research purposes only. We are not affiliated with any journal publishers and do not handle publication submissions. For publication-related inquiries, please contact the respective journal publishers directly.
If you notice any inaccuracies in the information displayed, please contact us at support@chemtradehub.com. We will promptly review and address your concerns.