Androsterone-based gels enable diastereospecific reductions and diastereoselective epoxidations of gelators
Literature Information
Tao Li, Yu Chen, Chunbao Li
Eleven new androsterone-based gelators were synthesized, and their gelation properties and gel-mediated reactions were investigated. The relationships between the structures, gelation and self-assembly processes of the gelators are discussed. By using granular PTFE (polytetrafluoroethylene) as costirrers, quantitative and diastereospecific reductions of the gelator carbonyl groups mediated by water were achieved in the gels of seven gelators. This reduction did not occur in the control experiment which used organic solvent-mediated conventional conditions. The diastereospecific and quantitative reductions possibly occur via a hydrogen-bonded-activated carbonyl mechanism. Five of the gelators underwent gel-mediated epoxidation and the products were more diastereoselective than those obtained using conventional epoxidation reactions. This can be attributed to the ordered arrangements in the gels.
Related Literature
Nucleophilicities and carbon basicities of DBU and DBN‡
M. Baidya, Herbert Mayr
DOI: 10.1039/B801811A
Angle-controlled arrangement of single-walled carbon nanotubes solubilised by 8-quinolinol metal chelate derivatives on mica
Kazuyuki Nobusawa, Atsushi Ikeda, Yasunori Tanaka, Mineo Hashizume, Jun-ichi Kikuchi, Michihiro Shirakawa, Tatsuya Kitahara, Norifumi Fujita, Seiji Shinkai
DOI: 10.1039/B715960A
Controlled regio- and chemoselective addition of isothiocyanate to the dione moiety of a cage-opened fullerene-mixed peroxide derivative
Zheming Wang
DOI: 10.1039/B800722E
Sulfate ion encapsulation in caged supramolecular structures assembled by second-sphere coordination
Jianjun Liang, Jin Yang, Chuandong Jia, Hongrui Zhang, Ning Tang, Christoph Janiak
DOI: 10.1039/B719019K
Single molecule conformational analysis of the biologically relevant DNA G-quadruplex in the promoter of the proto-oncogene c-MYC
Pravin S. Shirude, Liming Ying, Shankar Balasubramanian
DOI: 10.1039/B801465E
Phase-transfer catalytic aza-Michael addition of tert-butyl benzyloxycarbamate to electron-deficient olefins
Jihoon Lee, Mi-hyun Kim, Sang-sup Jew, Hyeung-geun Park, Byeong-Seon Jeong
DOI: 10.1039/B800130H
Cu-catalyzed stereoselective conjugate addition of arylboronic acids to alkynoates
Yoshihiko Yamamoto, Naohiro Kirai, Yu Harada
DOI: 10.1039/B802231C
Fast energy transfer within a self-assembled cyclic porphyrin tetramer
DOI: 10.1039/B718628B
Use of ionic liquids (ILs) for the IL-anion size-dependent formation of Cr, Mo and W nanoparticles from metal carbonyl M(CO)6 precursors
Engelbert Redel, Ralf Thomann, Christoph Janiak
DOI: 10.1039/B718055A
Inhibition and dispersion of proteobacterial biofilms
Justin J. Richards, Robert W. Huigens III, T. Eric Ballard, Anne Basso, John Cavanagh, Christian Melander
DOI: 10.1039/B719802G
You might also like
What is the market or research trend for N-(4-Methoxybenzyl)-2-pyridinamine (CAS: 52818-63-0)?
N-(4-Methoxybenzyl)-2-pyridinamine (CAS: 52818-63-0) is increasingly being used ...
What precautions should be taken when handling Ethyl 4-(2-chlorophenyl)-1,3-thiazole-2-carboxylate (CAS: 1050507-06-6)?
When handling Ethyl 4-(2-chlorophenyl)-1,3-thiazole-2-carboxylate, appropriate p...
What regulatory guidelines apply to diethyldiselane (CAS: 628-39-7)?
Diethyldiselane (CAS: 628-39-7) is classified under the Globally Harmonized Syst...
What is the market or research trend for oxocopper (CAS: 12053-18-8)?
The market for oxocopper (CAS: 12053-18-8) is primarily driven by its use in cat...
What is the market or research trend for 5-{[(2-Methyl-2-propanyl)oxy]carbonyl}-5-azaspiro[2.4]heptane-7-carboxylic acid?
The market for 5-{[(2-Methyl-2-propanyl)oxy]carbonyl}-5-azaspiro[2.4]heptane-7-c...
What is 2-(1-Pyrrolidinyl)-4-pyridinamine (CAS: 35981-63-6)?
2-(1-Pyrrolidinyl)-4-pyridinamine is a chemical compound with the CAS number 359...
What are the physical and chemical properties of 2-(3-Pyridinyl)-1-azabicyclo[2.2.2]octane (CAS: 91556-75-1)?
2-(3-Pyridinyl)-1-azabicyclo[2.2.2]octane (CAS: 91556-75-1) is a crystalline sol...
How is (S)-Alpha-allyl-proline hydrochloride (CAS: 129704-91-2) typically synthesized?
(S)-Alpha-allyl-proline hydrochloride is usually synthesized via a Wittig reacti...
What is 3-Methyl-1,2-oxazole-5-carboxylic acid (CAS: 4857-42-5)?
3-Methyl-1,2-oxazole-5-carboxylic acid (CAS: 4857-42-5) is an organic compound w...
How is Lys-SMCC-DM1 (CAS: 1281816-04-3) typically synthesized?
Lys-SMCC-DM1 is synthesized via a multi-step process involving the coupling of S...
Source Journal
Organic & Biomolecular Chemistry

Organic & Biomolecular Chemistry (OBC) publishes original and high impact research and reviews in organic chemistry. We welcome research that shows new or significantly improved protocols or methodologies in total synthesis, synthetic methodology or physical and theoretical organic chemistry as well as research that shows a significant advance in the organic chemistry or molecular design aspects of chemical biology, catalysis, supramolecular and macromolecular chemistry, theoretical chemistry, mechanism-oriented physical organic chemistry, medicinal chemistry or natural products. Articles published in the journal should report new work which makes a highly-significant impact in the field. Routine and incremental work is generally not suitable for publication in the journal. More details about key areas of our scope are below. In all cases authors should include in their article clear rationale for why their research has been carried out.










![5'-Fluoro-[2,3'-biindolinylidene]-2',3-dione structure 5'-Fluoro-[2,3'-biindolinylidene]-2',3-dione structure](https://static.chemtradehub.com/structs/251/251903-00-1-9cb1.webp)



![1-oxaspiro[4.4]nonan-6-one structure 1-oxaspiro[4.4]nonan-6-one structure](https://static.chemtradehub.com/structs/134/134179-01-4-e051.webp)