AIE conjugated polyelectrolytes based on tetraphenylethene for efficient fluorescence imaging and lifetime imaging of living cells

Literature Information

Publication Date 2017-06-05
DOI 10.1039/C7PY00564D
Impact Factor 5.582
Authors

Mengxia Gao, Bin Chen, Yinan Wang, Wenjun Zhou, Wallace W. H. Wong, Trevor A. Smith, Zujin Zhao


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Abstract

A series of new conjugated polyelectrolytes (CPEs) containing tetraphenylethene units are synthesized and characterized. They show apparent aggregation-induced emission (AIE) characteristics and give fluorescence covering from cyan to red with high emission efficiencies in aggregates. These AIE CPEs can directly enter and stain living cells for fluorescence imaging with low cytotoxicity, and can provide information on cellular viscosity at different locations based on fluorescence lifetime imaging.

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Polymer Chemistry

Polymer Chemistry
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