Eosin Y photoredox catalyzed net redox neutral reaction for regiospecific annulation to 3-sulfonylindoles via anion oxidation of sodium sulfinate salts
Literature Information
Shrikant D. Tambe, Umesh A. Kshirsagar
An eosin Y photoredox catalyzed net redox neutral process for 3-sulfonylindoles via the anionic oxidation of sodium sulfinate salts and its radical cascade cyclization with 2-alkynyl-azidoarenes was developed with visible light as a mediator. The reaction offers metal and oxidant/reductant free, visible light mediated vicinal sulfonamination of alkynes to 2-aryl/alkyl-3-sulfonylindoles and proceeds via the generation of a sulfur-centered radical through direct oxidation of the sulfinate anion by an excited photocatalyst with a reductive quenching cycle. The mild conditions, use of an organic dye as photo-catalyst, bench stability and easily accessible starting materials make the present approach green and attractive.
Recommended Journals

Russian Journal of Bioorganic Chemistry

Saudi Pharmaceutical Journal

Journal of Natural Medicines

Nature Medicine

Current Opinion in Solid State & Materials Science

Russian Journal of Coordination Chemistry

Russian Journal of Applied Chemistry

Crystallography Reports

Organic Process Research & Development

Drug Discovery Today
Related Literature
Magnetic properties of a doped linear polyarylamine bearing a high concentration of coupled spins (S = 1)
Vincent Maurel, Mohammad Jouni, Piotr Baran, Nicolas Onofrio, Serge Gambarelli, Jean-Marie Mouesca, David Djurado, Lionel Dubois, Jean-François Jacquot, Gérard Desfonds, Irena Kulszewicz-Bajer
DOI: 10.1039/C1CP22766A
Lyotropic liquid crystalline phase behaviour in amphiphile–protic ionic liquid systems
Tamar L. Greaves, Celesta Fong, Calum J. Drummond
DOI: 10.1039/C2CP23698B
Cooperative effect of temperature and linker functionality on CO2 capture from industrial gas mixtures in metal–organic frameworks: a combined experimental and molecular simulation study
Wenjuan Zhang, Hongliang Huang, Chongli Zhong, Dahuan Liu
DOI: 10.1039/C2CP23839J
The interaction of His337 with the Mn4Ca cluster of photosystem II
Simon Petrie, Phillip Gatt, Robert Stranger, Ron J. Pace
DOI: 10.1039/C2CP23935C
Mechanism of photocatalytic activities in Cr-doped SrTiO3 under visible-light irradiation: an insight from hybrid density-functional calculations
Pakpoom Reunchan, Shuxin Ouyang
DOI: 10.1039/C2CP23348G
Influence of a charged graphene surface on the orientation and conformation of covalently attached oligonucleotides: a molecular dynamics study
O. Kroutil, M. Předota, F. Lankaš, M. Šíp
DOI: 10.1039/C2CP23540D
A general strategy for the experimental study of the thermochemistry of protic ionic liquids: enthalpy of formation and vaporisation of 1-methylimidazolium ethanoate
Joana Vitorino, Manuel E. Minas da Piedade
DOI: 10.1039/C2CP40213K
You might also like
What are the main uses of (3.beta.)-3-Hydroxy-N,N-dimethyl-chol-5-en-24-amide (CAS: 79066-03-8)?
(3.beta.)-3-Hydroxy-N,N-dimethyl-chol-5-en-24-amide (CAS: 79066-03-8) is primari...
What regulatory guidelines apply to 5-(aminomethyl)-2-methoxyphenol (CAS: 89702-89-6)?
5-(Aminomethyl)-2-methoxyphenol (CAS: 89702-89-6) is classified under GHS as a s...
What is Thieno[2,3-c]pyridin-7(6H)-one (CAS: 28981-13-7)?
Thieno[2,3-c]pyridin-7(6H)-one (CAS: 28981-13-7) is a heterocyclic organic compo...
Is 1-[(6-Methoxy-3-pyridinyl)methyl]-4-piperidinamine dihydrochloride (CAS: 1185311-28-7) safe?
1-[(6-Methoxy-3-pyridinyl)methyl]-4-piperidinamine dihydrochloride is generally ...
What regulatory guidelines apply to [(2E)-3-Phenyl-2-propen-1-yl]phosphonic acid (CAS: 146404-58-2)?
[(2E)-3-Phenyl-2-propen-1-yl]phosphonic acid (CAS: 146404-58-2) is regulated und...
What regulatory guidelines apply to 6-Bromo-7-methoxyquinoline (CAS: 1620515-86-7)?
6-Bromo-7-methoxyquinoline (CAS: 1620515-86-7) falls under the scope of the Glob...
What industries use (2R)-1-(1-Benzofuran-2-yl)-N-propyl-2-pentanamine (CAS: 260550-89-8)?
This compound is primarily used in the pharmaceutical industry for the developme...
What are the main uses of 1-Ethyl-7-[2-methyl-6-(4H-1,2,4-triazol-3-yl)-3-pyridinyl]-3,5-dihydropyrazino[2,3-b]pyrazin-2(1H)-one (CAS: 1228013-15-7)?
1-Ethyl-7-[2-methyl-6-(4H-1,2,4-triazol-3-yl)-3-pyridinyl]-3,5-dihydropyrazino[2...
Are there alternatives to {5-(Acryloylamino)-2-[(dimethylamino)methyl]phenyl}boronic acid (CAS: 1217500-78-1) in synthesis?
Alternative reagents such as 2-[(dimethylamino)methyl]phenylboronic acid or rela...
What is 3-(Piperidin-4-yloxy)pyridine (CAS: 310881-48-2)?
3-(Piperidin-4-yloxy)pyridine (CAS: 310881-48-2) is an organic compound with the...
Source Journal
Organic & Biomolecular Chemistry

Organic & Biomolecular Chemistry (OBC) publishes original and high impact research and reviews in organic chemistry. We welcome research that shows new or significantly improved protocols or methodologies in total synthesis, synthetic methodology or physical and theoretical organic chemistry as well as research that shows a significant advance in the organic chemistry or molecular design aspects of chemical biology, catalysis, supramolecular and macromolecular chemistry, theoretical chemistry, mechanism-oriented physical organic chemistry, medicinal chemistry or natural products. Articles published in the journal should report new work which makes a highly-significant impact in the field. Routine and incremental work is generally not suitable for publication in the journal. More details about key areas of our scope are below. In all cases authors should include in their article clear rationale for why their research has been carried out.

![4,4-Difluoro-2-methyl-1-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-proline structure 4,4-Difluoro-2-methyl-1-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-proline structure](https://static.chemtradehub.com/structs/119/1194032-23-9-f426.webp)
![4-[(4-Bromophenyl)sulfonyl]thiomorpholine structure 4-[(4-Bromophenyl)sulfonyl]thiomorpholine structure](https://static.chemtradehub.com/structs/223/223555-81-5-2d67.webp)

