A fluorescent activatable probe for imaging intracellular Mg2+â€

Literature Information

Publication Date 2017-12-19
DOI 10.1039/C7OB02965A
Impact Factor 3.876
Authors

Ryan Treadwell, Fabio de Moliner, Ramon Subiros-Funosas, Toby Hurd, Kirsten Knox, Marc Vendrell


View Original

Abstract

An activatable BODIPY probe for in vitro detection and fluorescence cell imaging of free Mg2+ without interference from Ca2+ is described. Fluorescence amplification of the probe is observed upon detection of physiological concentrations of Mg2+ due to reduced rotation of the fluorophore and effective chelation by a quinolizine-based core.

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Organic & Biomolecular Chemistry
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