Palladium-catalyzed synthesis of fluoreones from bis(2-bromophenyl)methanols

Literature Information

Publication Date 2017-12-12
DOI 10.1039/C7OB02895D
Impact Factor 3.876
Authors

Qian Gao, Senmiao Xu


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Abstract

A palladium-catalyzed synthesis method of fluorenones has been developed. A variety of bis(2-bromophenyl)methanols could undergo the reaction smoothly in the presence of Pd(OAc)2, affording a series of fluorenones in moderate to good yields (two steps). Mechanistic studies reveal that the reaction might be triggered by oxidation of alcohol followed by intramolecular reductive coupling.

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Organic & Biomolecular Chemistry

Organic & Biomolecular Chemistry
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