![N-[(6-Bromo-3-pyridinyl)methyl]ethanamine structure](https://static.chemtradehub.com/structs/120/120740-05-8-ca55.webp "N-[(6-Bromo-3-pyridinyl)methyl]ethanamine structure")
Can strand displacement take place in DNA triplexes?
Literature Information
Publication Date
2017-12-21
DOI
10.1039/C7OB02871G
Impact Factor
3.876
Authors
Qian Li, Cheng Tian, Xiang Li, Chengde Mao
View Original
Abstract
This work studies strand displacement in the context of DNA triplexes. We observed that toehold-mediated strand displacement could proceed in DNA triplexes, but at a much slower rate than in DNA duplexes. In this study, strand displacement was studied with native polyacrylamide gel electrophoresis (PAGE) for two molecular systems. While both systems were involved in branch migration in a DNA triplex, the toehold forms either a duplex or a triplex. This study provides a new strategy for sequence-specific strand displacement and it is useful for the construction of dynamic DNA nanostructures and control of smart DNA nanodevices.
Related Literature
Fabrication of color changeable CO2 sensitive nanofibers
Jiaojiao Shang, Shaojian Lin, Patrick Theato
2017-11-16
Communication
DOI: 10.1039/C7PY01628J
Renewable polyols for advanced polyurethane foams from diverse biomass resources
Pierre Furtwengler, Luc Avérous
2018-07-24
Review Article
DOI: 10.1039/C8PY00827B
Inhibition of lysozyme's polymerization activity using a polymer structural mimic
D. L. Morris, T. C. Leeper, C. J. Ziegler
2018-05-29
Communication
DOI: 10.1039/C8PY00545A
Simultaneous superior lubrication and high load bearing by the dynamic weak interaction of a lubricant with mechanically strong bilayer porous hydrogels
Meirong Cai, Bo Yu, Feng Zhou
2017-10-03
Communication
DOI: 10.1039/C7PY01532A
Swelling properties of thermoresponsive/hydrophilic co-networks with functional crosslinked domain structures
Shohei Ida, Hironobu Kitanaka, Tatsuya Ishikawa, Shokyoku Kanaoka, Yoshitsugu Hirokawa
2018-01-03
Paper
DOI: 10.1039/C7PY01793F
Highly efficient luminescent side-chain polymers with short-spacer attached tetraphenylethylene AIEgens via RAFT polymerization capable of naked eye explosive detection
Qian Li, Xiao Li, Zhongying Wu, Yuhao Sun, Jianglin Fang, Dongzhong Chen
2018-07-02
Paper
DOI: 10.1039/C8PY00710A
You might also like
Compound Q&A
What are the main uses of (3.beta.)-3-Hydroxy-N,N-dimethyl-chol-5-en-24-amide (CAS: 79066-03-8)?
(3.beta.)-3-Hydroxy-N,N-dimethyl-chol-5-en-24-amide (CAS: 79066-03-8) is primari...
79066-03-8(3.beta.)-3-Hydroxy-...
Compound Q&A
What regulatory guidelines apply to 5-(aminomethyl)-2-methoxyphenol (CAS: 89702-89-6)?
5-(Aminomethyl)-2-methoxyphenol (CAS: 89702-89-6) is classified under GHS as a s...
89702-89-65-(aminomethyl)-2-me...
Compound Q&A
What is Thieno[2,3-c]pyridin-7(6H)-one (CAS: 28981-13-7)?
Thieno[2,3-c]pyridin-7(6H)-one (CAS: 28981-13-7) is a heterocyclic organic compo...
28981-13-7Thieno[2,3-c]pyridin...
Compound Q&A
Is 1-[(6-Methoxy-3-pyridinyl)methyl]-4-piperidinamine dihydrochloride (CAS: 1185311-28-7) safe?
1-[(6-Methoxy-3-pyridinyl)methyl]-4-piperidinamine dihydrochloride is generally ...
1185311-28-71-[(6-Methoxy-3-pyri...
Compound Q&A
What regulatory guidelines apply to [(2E)-3-Phenyl-2-propen-1-yl]phosphonic acid (CAS: 146404-58-2)?
[(2E)-3-Phenyl-2-propen-1-yl]phosphonic acid (CAS: 146404-58-2) is regulated und...
146404-58-2[(2E)-3-Phenyl-2-pro...
Compound Q&A
What regulatory guidelines apply to 6-Bromo-7-methoxyquinoline (CAS: 1620515-86-7)?
6-Bromo-7-methoxyquinoline (CAS: 1620515-86-7) falls under the scope of the Glob...
1620515-86-76-Bromo-7-methoxyqui...
Compound Q&A
What industries use (2R)-1-(1-Benzofuran-2-yl)-N-propyl-2-pentanamine (CAS: 260550-89-8)?
This compound is primarily used in the pharmaceutical industry for the developme...
260550-89-8(2R)-1-(1-Benzofuran...
Compound Q&A
What are the main uses of 1-Ethyl-7-[2-methyl-6-(4H-1,2,4-triazol-3-yl)-3-pyridinyl]-3,5-dihydropyrazino[2,3-b]pyrazin-2(1H)-one (CAS: 1228013-15-7)?
1-Ethyl-7-[2-methyl-6-(4H-1,2,4-triazol-3-yl)-3-pyridinyl]-3,5-dihydropyrazino[2...
1228013-15-71-Ethyl-7-[2-methyl-...
Compound Q&A
Are there alternatives to {5-(Acryloylamino)-2-[(dimethylamino)methyl]phenyl}boronic acid (CAS: 1217500-78-1) in synthesis?
Alternative reagents such as 2-[(dimethylamino)methyl]phenylboronic acid or rela...
1217500-78-1{5-(Acryloylamino)-2...
Compound Q&A
What is 3-(Piperidin-4-yloxy)pyridine (CAS: 310881-48-2)?
3-(Piperidin-4-yloxy)pyridine (CAS: 310881-48-2) is an organic compound with the...
310881-48-23-(Piperidin-4-yloxy...
Source Journal
Organic & Biomolecular Chemistry
CiteScore:
3.4
Self-citation Rate:
10.3%
Articles per Year:
1041
Organic & Biomolecular Chemistry (OBC) publishes original and high impact research and reviews in organic chemistry. We welcome research that shows new or significantly improved protocols or methodologies in total synthesis, synthetic methodology or physical and theoretical organic chemistry as well as research that shows a significant advance in the organic chemistry or molecular design aspects of chemical biology, catalysis, supramolecular and macromolecular chemistry, theoretical chemistry, mechanism-oriented physical organic chemistry, medicinal chemistry or natural products. Articles published in the journal should report new work which makes a highly-significant impact in the field. Routine and incremental work is generally not suitable for publication in the journal. More details about key areas of our scope are below. In all cases authors should include in their article clear rationale for why their research has been carried out.
Recommended Compounds
amine structure](https://static.chemtradehub.com/structs/629/62924-61-2-0728.webp "[(2-chlorophenyl)methyl](ethyl)amine structure")
Recommended Suppliers
Disclaimer
This page provides academic journal information for reference and research purposes only. We are not affiliated with any journal publishers and do not handle publication submissions. For publication-related inquiries, please contact the respective journal publishers directly.
If you notice any inaccuracies in the information displayed, please contact us at support@chemtradehub.com. We will promptly review and address your concerns.