Dendrimeric amide- and carbamate-linked lysine-based efficient molecular transporters

Literature Information

Publication Date 2017-10-30
DOI 10.1039/C7OB02552A
Impact Factor 3.876
Authors

Namit Dey, Sabyasachi Chattopadhyay


View Original

Abstract

Amide- and carbamate-linked dendrimeric oligomers are reported as molecular transporters. They effectively complex with pDNA and transport it into cells at an efficiency superior to Lipofectamine, when complexation is carried out by incubation overnight. The carbamate-linked K2C is superior to amide-linked K2A; their pDNA complexes have very low associated cytotoxicity.

Related Literature

Direct syntheses of functionalized mesostructured silica by using an inexpensive silica source‡

Robert J. P. Corriu, Ahmad Mehdi, Catherine Reyé, Chloé Thieuleux

2004-05-19 Communication

DOI: 10.1039/B314415A

New, highly acidic ionic liquid systems and their application in the carbonylation of toluene

Nicole Brausch, Andreas Metlen, Peter Wasserscheid

2004-05-21 Communication

DOI: 10.1039/B403464C

Novel cobalt-free oxygen permeable membrane

Xuefeng Zhu, Haihui Wang, Weishen Yang

2004-04-08 Communication

DOI: 10.1039/B400857J

[2 + 2]Photocyclization in a single-crystal-to-single-crystal transformation of a TTF-amido-pyridine

Thomas Devic, Patrick Batail, Narcis Avarvari

2004-05-25 Communication

DOI: 10.1039/B404482G

Molecularly imprinted polymer sensor arrays

Nathaniel T. Greene, Stephen L. Morgan, Ken D. Shimizu

2004-04-28 Communication

DOI: 10.1039/B401677G

Halide anion directed assembly of luminescent pseudorotaxanes

David Curiel, Paul D. Beer, Rowena L. Paul, Andrew Cowley, Mark R. Sambrook, Fridrich Szemes

2004-04-22 Communication

DOI: 10.1039/B401900H

Programmed single step self-assembly of a [2 × 2] grid architecture built on metallic centers of different coordination geometries

Anne Petitjean, Nathalie Kyritsakas, Jean-Marie Lehn

2004-04-23 Communication

DOI: 10.1039/B402854F

K6Cd4Sn3Se13: A polar open-framework compound based on the partially destroyed supertetrahedral [Cd4Sn4Se17]10− cluster

Nan Ding, Duck-Young Chung, Mercouri G. Kanatzidis

2004-04-23 Communication

DOI: 10.1039/B402686A

Efficient synthesis of a nucleoside-diphospho-exo-glycal displaying time-dependent inactivation of UDP-galactopyranose mutase

Audrey Caravano, Stéphane P. Vincent, Pierre Sinaÿ

2004-04-23 Communication

DOI: 10.1039/B402469A

The first tandem double palladium-catalyzed aminations: synthesis of dipyrido[1,2-a∶3′,2′-d]imidazole and its benzo- and aza-analogues

Kristof T. J. Loones, Bert U. W. Maes, Roger A. Dommisse, Guy L. F. Lemière

2004-09-20 Communication

DOI: 10.1039/B409161B

You might also like

Compound Q&A

What precautions should be taken when handling 2-Chloro-1,2-bis(4-methylphenyl)ethanone (CAS: 71193-32-3)?

When handling 2-Chloro-1,2-bis(4-methylphenyl)ethanone (CAS: 71193-32-3), it is ...

71193-32-32-Chloro-1,2-bis(4-m...
Compound Q&A

What industries use 4-Ethoxy-3-(5-methyl-4-oxo-7-propyl-1,4-dihydroimidazo[5,1-f][1,2,4]triazin-2-yl)benzenesulfonyl chloride (CAS: 224789-26-8)?

4-Ethoxy-3-(5-methyl-4-oxo-7-propyl-1,4-dihydroimidazo[5,1-f][1,2,4]triazin-2-yl...

224789-26-84-Ethoxy-3-(5-methyl...
Compound Q&A

How should Methyl 3-Oxo-4-Androsten-17-Carboxylate (CAS: 2681-55-2) be stored?

Methyl 3-Oxo-4-Androsten-17-Carboxylate (CAS: 2681-55-2) should be stored in a c...

2681-55-2Methyl 3-Oxo-4-Andro...
Compound Q&A

What are the main uses of (R)-3-Amino-4-(3-hexylphenylamino)-4-oxobutylphosphonic acid (CAS: 909725-61-7)?

(R)-3-Amino-4-(3-hexylphenylamino)-4-oxobutylphosphonic acid is primarily used i...

909725-61-7(R)-3-Amino-4-(3-hex...
Compound Q&A

What regulatory guidelines apply to 2-Methyl-2-propanyl 3-amino-3-carbamoyl-1-azetidinecarboxylate (CAS: 1254120-14-3)?

2-Methyl-2-propanyl 3-amino-3-carbamoyl-1-azetidinecarboxylate (CAS: 1254120-14-...

1254120-14-32-Methyl-2-propanyl ...
Compound Q&A

Are there alternatives to (E)-4-(tert-Butoxy)-4-oxobut-2-enoic acid (CAS: 135355-96-3) in synthesis?

There are alternative reagents that can be used in synthesis instead of (E)-4-(t...

135355-96-3(E)-4-(tert-Butoxy)-...
Compound Q&A

What are the physical and chemical properties of [2-(3-Chlorophenyl)-1,3-thiazol-4-yl]methanol (CAS: 121202-20-8)?

[2-(3-Chlorophenyl)-1,3-thiazol-4-yl]methanol (CAS: 121202-20-8) is a crystallin...

121202-20-8[2-(3-Chlorophenyl)-...
166249-17-8Methyl (2S)-[(4S)-2,...
Compound Q&A

What is the market or research trend for 1-Bromo-2-isocyanatoethane (CAS: 42865-19-0)?

The market for 1-Bromo-2-isocyanatoethane (CAS: 42865-19-0) is driven by its use...

42865-19-01-Bromo-2-isocyanato...
Compound Q&A

What are the main uses of 4-Nitro-D-phenylalanine hydrochloride (CAS: 147065-06-3)?

4-Nitro-D-phenylalanine hydrochloride (CAS: 147065-06-3) is primarily used in re...

147065-06-34-Nitro-D-phenylalan...

Source Journal

Organic & Biomolecular Chemistry

Organic & Biomolecular Chemistry
CiteScore: 3.4
Self-citation Rate: 10.3%
Articles per Year: 1041

Organic & Biomolecular Chemistry (OBC) publishes original and high impact research and reviews in organic chemistry. We welcome research that shows new or significantly improved protocols or methodologies in total synthesis, synthetic methodology or physical and theoretical organic chemistry as well as research that shows a significant advance in the organic chemistry or molecular design aspects of chemical biology, catalysis, supramolecular and macromolecular chemistry, theoretical chemistry, mechanism-oriented physical organic chemistry, medicinal chemistry or natural products. Articles published in the journal should report new work which makes a highly-significant impact in the field. Routine and incremental work is generally not suitable for publication in the journal. More details about key areas of our scope are below. In all cases authors should include in their article clear rationale for why their research has been carried out.

Recommended Compounds

Recommended Suppliers

Disclaimer
This page provides academic journal information for reference and research purposes only. We are not affiliated with any journal publishers and do not handle publication submissions. For publication-related inquiries, please contact the respective journal publishers directly.
If you notice any inaccuracies in the information displayed, please contact us at support@chemtradehub.com. We will promptly review and address your concerns.