Efficient synthesis of a nucleoside-diphospho-exo-glycal displaying time-dependent inactivation of UDP-galactopyranose mutase

Literature Information

Publication Date 2004-04-23
DOI 10.1039/B402469A
Impact Factor 6.222
Authors

Audrey Caravano, Stéphane P. Vincent, Pierre Sinaÿ


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Abstract

A short and efficient synthesis of UDP-exo-galactofuranosyl-glycal is presented. This molecule displayed an interesting time-dependent inactivation of UDP-galactopyranose mutase, an essential enzyme of the mycobacterial cell wall biosynthesis.

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