One step construction of a taxane-like skeleton by a diendiyne metathesis cyclization reaction‡

Literature Information

Publication Date 2016-12-26
DOI 10.1039/C6QO00741D
Impact Factor 5.281
Authors

J. Otero-Fraga, J. R. Granja


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Abstract

One-step cyclization for the formation of the characteristic tricyclic system of taxanes is described. This process is based on a cascade metathesis cyclization reaction that allows the preparation of novel taxane derivatives in a fast and simple manner.

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Organic Chemistry Frontiers publishes high-quality research from across organic chemistry. Emphases are placed on studies that make significant contributions to the field of organic chemistry by reporting either new or significantly improved protocols or methodologies. Topics include, but are not limited to the following: Organic synthesis Development of synthetic methodologies Catalysis Natural products Functional organic materials Supramolecular and macromolecular chemistry Physical and computational organic chemistry

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