Aqueous MCRs of quaternary ammoniums, N-substituted formamides and sodium disulfide towards aryl thioamides
Literature Information
Publication Date
2016-12-19
DOI
10.1039/C6QO00670A
Impact Factor
5.281
Authors
Zhou Zhou, Jin-Tao Yu, Yongnan Zhou, Yan Jiang, Jiang Cheng
View Original
Abstract
A three-component reaction of quaternary ammonium salts, N-substituted formamides and aqueous sodium disulfide was developed, leading to aryl/heteroaryl thioamides in moderate to good yields with good functional group compatibility. This procedure was featured with the combination of three reaction partners, rendering an important complementary to the previously reported methods for the synthesis of aryl thioamides, and was beneficial to the chemistry of functional group transformations. No external oxidant was required in this procedure.
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Organic Chemistry Frontiers
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7.8
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Organic Chemistry Frontiers publishes high-quality research from across organic chemistry. Emphases are placed on studies that make significant contributions to the field of organic chemistry by reporting either new or significantly improved protocols or methodologies. Topics include, but are not limited to the following: Organic synthesis Development of synthetic methodologies Catalysis Natural products Functional organic materials Supramolecular and macromolecular chemistry Physical and computational organic chemistry
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