Acid-promoted denitrogenative Pd-catalyzed addition of arylhydrazines with nitriles at room temperature

Literature Information

Publication Date 2016-12-13
DOI 10.1039/C6QO00634E
Impact Factor 5.281
Authors

Kai Cheng, Guofang Wang, Mengting Meng, Chenze Qi


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Abstract

The Pd(TFA)2-catalyzed denitrogenative addition proceeded with selective C–N bond cleavage of arylhydrazines with nitriles in the presence of DABCO and HFBA under air at room temperature. Aryl ketones could be easily synthesized via the hydrolysis of the ketimine moiety generated in situ without the need for additional water.

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