Glyconanoparticles with controlled morphologies and their interactions with a dendritic cell lectin

Literature Information

Publication Date 2016-09-30
DOI 10.1039/C6PY01523A
Impact Factor 5.582
Authors

Lea Messager, Anne S. Gleinich, Daniel A. Mitchell, Giuseppe Battaglia, C. Remzi Becer


View Original

Abstract

Well-defined amphiphilic block glycopolymers with equal mannose content have been self-assembled in aqueous solution to form glyconanoparticles with different morphologies. The size and shape of nanoparticles have significant effects on the interactions with the dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin (DC-SIGN; CD209), characterized using a surface plasmon resonance spectrometer (SPR).

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