![1-[4-(4-Methyl-1H-imidazol-1-yl)phenyl]ethanone structure](https://static.chemtradehub.com/structs/142/142161-53-3-7f55.webp "1-[4-(4-Methyl-1H-imidazol-1-yl)phenyl]ethanone structure")
An array of individually addressable micro-needles for mapping pH distributions
Literature Information
Publication Date
2016-05-11
DOI
10.1039/C6AN00639F
Impact Factor
4.616
Authors
Claudio Zuliani, Fu Siong Ng, Andrea Alenda, Amir Eftekhar, Nicholas S. Peters, Christofer Toumazou
View Original
Abstract
This work describes the preparation of an array of individually addressable pH sensitive microneedles which are sensitized by electrodepositing iridium oxide. The impact of the deposition potential, storage conditions and interferents on the sensor characteristics such as slope, offset, intra- and inter-batch reproducibility is investigated. The device may be a useful tool for carrying out direct pH measurements of soft and heterogeneous samples such as tissues and organs. For example, we demonstrated that the microneedle array can be employed for real-time mapping of the cardiac pH distribution during cycles of global ischemia and reperfusion.
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Source Journal
Analyst
CiteScore:
7.8
Self-citation Rate:
5.6%
Articles per Year:
653
Analyst publishes analytical and bioanalytical research that reports premier fundamental discoveries and inventions, and the applications of those discoveries, unconfined by traditional discipline barriers.
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