tert-Butyl 4-chloro-5-methoxypyridin-3-ylcarbamate
CAS Number:
1045858-17-0
Molecular Formula:
C11H15ClN2O3
A fully battery-powered inexpensive spectrophotometric system for high-sensitivity point-of-care analysis on a microfluidic chip
Literature Information
Publication Date
2016-04-20
DOI
10.1039/C6AN00370B
Impact Factor
4.616
Authors
Maowei Dou, Juan Lopez, Misael Rios, Oscar Garcia, Chuan Xiao, Michael Eastman, XiuJun Li
View Original
Abstract
A cost-effective ttery-powered pectrophotometric ystem (BASS) was developed for quantitative point-of-care (POC) analysis on a microfluidic chip. By using methylene blue as a model analyte, we first compared the performance of the BASS with a commercial spectrophotometric system, and further applied the BASS for loop-mediated isothermal amplification (LAMP) detection and subsequent quantitative nucleic acid analysis which exhibited a comparable limit of detection to that of Nanodrop. Compared to the commercial spectrophotometric system, our spectrophotometric system is lower-cost, consumes less reagents, and has higher detection sensitivity. Most importantly, it does not rely on external power supplies. All these features make our spectrophotometric system highly suitable for a variety of POC analyses, such as field detection.
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Source Journal
Analyst
CiteScore:
7.8
Self-citation Rate:
5.6%
Articles per Year:
653
Analyst publishes analytical and bioanalytical research that reports premier fundamental discoveries and inventions, and the applications of those discoveries, unconfined by traditional discipline barriers.
Recommended Compounds
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1-(2-Chlorophenyl)-6-[(2S)-3,3,3-trifluoro-2-methylpropyl]-1,7-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one
CAS Number:
794568-91-5
Molecular Formula:
C15H12ClF3N4O
![2-morpholino-2-[2-(trifluoromethyl)pyrimidin-5-yl]ethanamine structure](https://static.chemtradehub.com/structs/119/1192570-20-9-2810.webp "2-morpholino-2-[2-(trifluoromethyl)pyrimidin-5-yl]ethanamine structure")
2-morpholino-2-[2-(trifluoromethyl)pyrimidin-5-yl]ethanamine
CAS Number:
1192570-20-9
Molecular Formula:
C11H15F3N4O
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