Carboxylate-assisted ruthenium(ii)-catalyzed C–H activations of monodentate amides with conjugated alkenes

Literature Information

Publication Date 2015-06-18
DOI 10.1039/C5QO00167F
Impact Factor 5.281
Authors

Jie Li, Lutz Ackermann


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Abstract

Carboxylate assistance enabled efficient and chemoselective ruthenium(II)-catalyzed hydroarylations of α,β-unsaturated ketones via C–H activation on monodentate benzamides. Furthermore, the versatile ruthenium(II) catalyst set the stage for oxidative C–H functionalization on acetanilides, furnishing diversely decorated quinolines in a step-economical fashion.

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Organic Chemistry Frontiers

Organic Chemistry Frontiers
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Organic Chemistry Frontiers publishes high-quality research from across organic chemistry. Emphases are placed on studies that make significant contributions to the field of organic chemistry by reporting either new or significantly improved protocols or methodologies. Topics include, but are not limited to the following: Organic synthesis Development of synthetic methodologies Catalysis Natural products Functional organic materials Supramolecular and macromolecular chemistry Physical and computational organic chemistry

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