Cu-catalyzed sp3 C–H bond oxidative functionalization of alkylazaarenes and substituted ethanones: an efficient approach to isoxazoline derivatives

Literature Information

Publication Date 2015-03-27
DOI 10.1039/C5QO00053J
Impact Factor 5.281
Authors

Gang-Wei Wang, Shi-Xia Li, Quan-Xiang Wu


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Abstract

Cu-catalyzed sp3 C–H bond oxidative functionalization of alkylazaarenes and substituted ethanones to different kinds of isoxazoline derivatives by 1,3-dipolar cycloaddition is reported. Cheap sources of nitro, commercially available substrates, as well as a variety of alkenes (alkynes) are applied in this transformation.

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Organic Chemistry Frontiers

Organic Chemistry Frontiers
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Organic Chemistry Frontiers publishes high-quality research from across organic chemistry. Emphases are placed on studies that make significant contributions to the field of organic chemistry by reporting either new or significantly improved protocols or methodologies. Topics include, but are not limited to the following: Organic synthesis Development of synthetic methodologies Catalysis Natural products Functional organic materials Supramolecular and macromolecular chemistry Physical and computational organic chemistry

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