The Mitsunobu reaction in the 21st century
Literature Information
Publication Date
2015-03-17
DOI
10.1039/C5QO00016E
Impact Factor
5.281
Authors
View Original
Abstract
The Mitsunobu reaction was first described almost fifty years ago and has enjoyed immense popularity since its inception. The purpose of this review is to focus on the more recent advances and applications of Mitsunobu chemistry, particularly from the 1990s to the present day. In addition to a discussion of newer reagents that facilitate purification, we will describe more contemporary applications of this chemistry, especially as applied to the synthesis of pharmaceuticals and their precursors.
Related Literature
Diastereoselective 1,2-difunctionalization of 1,3-enynes enabled by merging photoexcited Hantzsch ester with chromium catalysis
Jia Wu, Xiangyun Xu, Chongwen Duan, Shan Chen, Dan Wang, Likui Fang, Weiyang Tang, Fusheng Li
2023-10-20
Research Article
DOI: 10.1039/D3QO01522J
Correction: A facile, one-pot reductive alkylation of aromatic and heteroaromatic amines in aqueous micellar media: a chemoenzymatic approach
Ganesh Sambasivam, Karthikeyan Sivashanmugam
2023-11-03
Correction
DOI: 10.1039/D3OB90144K
Porphyrin- and Bodipy-helicene conjugates: syntheses, separation of enantiomers and chiroptical properties
Vincent Silber, Marion Jean, Nicolas Vanthuyne, Natalia Del Rio, Paola Matozzo, Jeanne Crassous, Romain Ruppert
2023-10-25
Paper
DOI: 10.1039/D3OB01459B
Hydantoin hexameric rosettes: harnessing H-bonds for supergelation and liquid crystals
Lucía González, Iván Marín, Rosa M. Tejedor, Joaquín Barberá, Pilar Romero, Alberto Concellón, Santiago Uriel, José L. Serrano
2023-12-04
Research Article
DOI: 10.1039/D3QO01832F
Copper-catalyzed crosscoupling of vinyl nitrenes and CF3-carbenes to synthesize CF3-2-azadienes
Yongjuan Jiao, Tao Wu, Xinyu Zhang
2023-11-07
Research Article
DOI: 10.1039/D3QO01537H
Olefination of aldehydes with alpha-halo redox-active esters
Zhengqiang Liu, Wenbo H. Liu
2023-12-14
Research Article
DOI: 10.1039/D3QO01805A
Mn-electrocatalytic oxidative C(sp3)–H azidation of 2-oxindoles and β-keto esters and azidation–cyclization of tryptamines
Shiwen Fan, Runxia Ma, Aohua Yang, Hongbo Jia, Yufei Dong, Cheng Guo, Jingyun Ren
2023-11-22
Research Article
DOI: 10.1039/D3QO01716H
Serine-mediated hydrazone ligation displaying insulin-like peptides on M13 phage pIII
Nan Zheng, Danny Hung-Chieh Chou
2023-10-24
Paper
DOI: 10.1039/D3OB01487H
Photoredox-catalyzed intramolecular oxy- and aminoacylation of alkenes with acyl oxime esters: facile synthesis of acylated saturated heterocycles
Min Wang, Liang-Chen Ren, Yu-Rui Jian, Xin-Yu Fu, Hong-Yu Zheng, Xiao Zha
2023-11-17
Research Article
DOI: 10.1039/D3QO01659E
You might also like
Compound Q&A
How should 2-Methylbenzene-1,4-diamine dihydrochloride (CAS: 615-45-2) be stored?
2-Methylbenzene-1,4-diamine dihydrochloride (CAS: 615-45-2) should be stored in ...
615-45-22-Methylbenzene-1,4-...
Compound Q&A
Is (1S,4S)-2,5-Diazabicyclo[2.2.1]heptane dihydrobromide (CAS: 132747-20-7) safe?
(1S,4S)-2,5-Diazabicyclo[2.2.1]heptane dihydrobromide is generally considered sa...
132747-20-7(1S,4S)-2,5-Diazabic...
Compound Q&A
What industries use (6-Chloropyridazin-3-YL)methanamine (CAS: 871826-15-2)?
(6-Chloropyridazin-3-YL)methanamine finds applications in the pharmaceutical ind...
871826-15-2(6-Chloropyridazin-3...
Compound Q&A
What are the main uses of 2-Fluoro-3-methylphenol (CAS: 77772-72-6)?
2-Fluoro-3-methylphenol is primarily used in the synthesis of pharmaceuticals, p...
77772-72-62-Fluoro-3-methylphe...
Compound Q&A
What precautions should be taken when handling 3-Methoxy-4-nitrobenzonitrile (CAS: 177476-75-4)?
When handling 3-Methoxy-4-nitrobenzonitrile, it is important to wear appropriate...
177476-75-43-Methoxy-4-nitroben...
Compound Q&A
What precautions should be taken when handling 1,3-Oxazolo[4,5-b]pyridine-2(3H)-thione (CAS: 211949-57-4)?
When handling 1,3-Oxazolo[4,5-b]pyridine-2(3H)-thione (CAS: 211949-57-4), it is ...
211949-57-4[1,3]Oxazolo[4,5-b]p...
Compound Q&A
What regulatory guidelines apply to 4-Ethynylbenzamide (CAS: 90347-86-7)?
4-Ethynylbenzamide (CAS: 90347-86-7) falls under various regulatory guidelines i...
90347-86-74-Ethynylbenzamide
Compound Q&A
What are the main uses of 3-(2-Ethylphenyl)-2-thioxo-4-imidazolidinone (CAS: 186822-57-1)?
3-(2-Ethylphenyl)-2-thioxo-4-imidazolidinone is primarily used as an intermediat...
186822-57-13-(2-Ethylphenyl)-2-...
Compound Q&A
What is (2-Fluoro-6-methoxyphenyl)acetic acid (CAS: 500912-19-6)?
(2-Fluoro-6-methoxyphenyl)acetic acid, also known as 4-fluoro-3-methoxybenzoic a...
500912-19-6(2-Fluoro-6-methoxyp...
Compound Q&A
What is the market or research trend for 2-[4-(Hydroxymethyl)phenoxy]ethanol (CAS: 102196-18-9)?
Market trends for 2-[4-(Hydroxymethyl)phenoxy]ethanol (CAS: 102196-18-9) indicat...
102196-18-92-[4-(Hydroxymethyl)...
Source Journal
Organic Chemistry Frontiers
CiteScore:
7.8
Self-citation Rate:
8.7%
Articles per Year:
724
Organic Chemistry Frontiers publishes high-quality research from across organic chemistry. Emphases are placed on studies that make significant contributions to the field of organic chemistry by reporting either new or significantly improved protocols or methodologies. Topics include, but are not limited to the following: Organic synthesis Development of synthetic methodologies Catalysis Natural products Functional organic materials Supramolecular and macromolecular chemistry Physical and computational organic chemistry
Recommended Compounds
![[(5-Methyl-1,3,4-thiadiazol-2-yl)sulfanyl]acetic acid structure](https://static.chemtradehub.com/structs/509/50918-26-8-4ce8.webp "[(5-Methyl-1,3,4-thiadiazol-2-yl)sulfanyl]acetic acid structure")
[(5-Methyl-1,3,4-thiadiazol-2-yl)sulfanyl]acetic acid
CAS Number:
50918-26-8
Molecular Formula:
C5H6N2O2S2
N-(5-Fluoro-2-oxo-2,3-dihydro-4-pyrimidinyl)benzamide
CAS Number:
10357-07-0
Molecular Formula:
C11H8FN3O2
Recommended Suppliers
Disclaimer
This page provides academic journal information for reference and research purposes only. We are not affiliated with any journal publishers and do not handle publication submissions. For publication-related inquiries, please contact the respective journal publishers directly.
If you notice any inaccuracies in the information displayed, please contact us at support@chemtradehub.com. We will promptly review and address your concerns.