Enhanced fluorescent resonant energy transfer of DNA conjugates complexed with surfactants and divalent metal ions

Literature Information

Publication Date 2016-03-08
DOI 10.1039/C5AN02516H
Impact Factor 4.616
Authors

Taeseok Oh, Jae-Young Choi


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Abstract

Dimerization and resultant quenching of donor and acceptor dyes conjugated on DNA causes loss of fluorescent resonant energy transfer (FRET) efficiency. However, when complexed with surfactants and divalent metal ions, sheathing effects insulate and shield the DNA structures, reducing dimerization and quenching which leads to significant enhancement of FRET efficiency.

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