Clean and efficient assembly of functionalized benzofuro[2,3-c]pyridines via metal-free one-pot domino reactions

Literature Information

Publication Date 2014-01-10
DOI 10.1039/C3GC42234H
Impact Factor 10.182
Authors

Yin Rao, Zhexian Li, Guodong Yin


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Abstract

A clean and efficient method for the domino synthesis of new functionalized benzofuro[2,3-c]pyridines from easily accessible 2-hydroxychalcones, α-bromo ketones and ammonium acetate is described. Furan and pyridine ring moieties are ingeniously formed in a one-pot operation in this tricyclic system.

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