Practical metal-free synthesis of chalcone derivatives via a tandem cross-dehydrogenative-coupling/elimination reaction

Literature Information

Publication Date 2013-08-27
DOI 10.1039/C3GC41403E
Impact Factor 10.182
Authors

Yu Wei, Jinghua Tang, Xuefeng Cong, Xiaoming Zeng


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Abstract

Metal-free synthesis of chalcone derivatives through a tandem cross-dehydrogenative-coupling/elimination reaction is described. A simple and inexpensive ammonium persulfate salt enables the reaction between ketones and benzylamines to proceed with high stereoselectivity and good functional group compatibility.

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