Optically pure bulky (hetero)arylalkyl carbinols via kinetic resolution
Literature Information
Bin Hu, Meng Meng, Weimin Mo, Xinquan Hu, Wei-Ping Deng
Planar chiral nucleophilic catalyst Fc-PIP was employed in the kinetic resolution of bulky (hetero)arylalkyl carbinols delivering unreacted alcohols with extremely high enantiomeric excess (>99.0% ees) in ideal conversions ranging from 50.4–56.7%.
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