Gold(i)-catalyzed synthesis of furans and pyrrolesviaalkyne hydration

Literature Information

Publication Date 2011-01-31
DOI 10.1039/C0CY00055H
Impact Factor 6.119
Authors

Pierrick Nun, Stéphanie Dupuy, Albert Poater, Luigi Cavallo, Steven P. Nolan


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Abstract

Furans and pyrroles were prepared via the gold(I)-catalyzed alkyne hydration of diynes. The use of [Au(IPr)OH] as precatalyst in a silver-free protocol permits low catalyst loadings and in situ generation of the active cationic gold species. A detailed computational study confirmed the experimental results and supports the proposed mechanism.

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Catalysis Science & Technology

Catalysis Science & Technology
CiteScore: 5.91
Self-citation Rate: 4.5%
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