Facile synthesis of stapled, structurally reinforced peptide helices via a photoinduced intramolecular 1,3-dipolar cycloaddition reaction

Literature Information

Publication Date 2009-08-13
DOI 10.1039/B912094G
Impact Factor 6.222
Authors

Michael M. Madden, Claudia I. Rivera Vera, Wenjiao Song, Qing Lin


View Original

Abstract

We report the first use of a photoinduced 1,3-dipolar cycloaddition reaction in “stapling” peptide sidechains to reinforce a model peptide helical structure with moderate to excellent yields; the resulting pyrazoline “staplers” exhibit unique fluorescence useful in a cell permeability study.

Related Literature

A vinylic rotaxane cross-linker for toughened network polymers from the radical polymerization of vinyl monomers

J. Sawada, D. Aoki, M. Kuzume, K. Nakazono, H. Otsuka, T. Takata

2017-02-13 Communication

DOI: 10.1039/C7PY00193B

Facile synthesis and chiral recognition of block and star copolymers containing stereoregular helical poly(phenyl isocyanide) and polyethylene glycol blocks

Na Liu, Cui-Hong Ma, Rui-Wen Sun, Jian Huang, Chonglong Li, Zong-Quan Wu

2017-03-09 Paper

DOI: 10.1039/C7PY00028F

A facile strategy to fabricate highly-stretchable self-healing poly(vinyl alcohol) hybrid hydrogels based on metal–ligand interactions and hydrogen bonding

Yan Hui, Zhi-Bin Wen, Florence Pilate, Hui Xie, Cheng-Jie Fan, Lan Du, Dan Liu, Ke-Ke Yang, Yu-Zhong Wang

2016-11-02 Paper

DOI: 10.1039/C6PY01752E

A high-performance dielectric block copolymer with a self-assembled superhelical nanotube morphology

Wenmei Liu, Jie Chen, Dandan Zhou, Xiaojuan Liao, Meiran Xie, Ruyi Sun

2016-12-05 Paper

DOI: 10.1039/C6PY01571A

Ferroelectric fluorinated copolymers with improved adhesion properties

Pedro Marcelino Dos Santos Filho, Vincent Ladmiral, Thierry Lannuzel, Fabrice Domingues Dos Santos, Bruno Améduri

2016-12-20 Paper

DOI: 10.1039/C6PY02063A

CO2 adsorption and catalytic application of imidazole ionic liquid functionalized porous organic polymers

Shuang Hao, Yuchuan Liu, Chuning Shang, Zhiqiang Liang, Jihong Yu

2017-02-27 Paper

DOI: 10.1039/C6PY02091G

Copolymerization of alkyl diazoacetates with α,β-unsaturated aldehydes: synthesis and application

Yan Li, Cheng Chen, Jinlong Wu, Xiangxiang Jia, Yufan Lu, Fangjuan Chen, Lijian Liu

2016-10-03 Paper

DOI: 10.1039/C6PY01666A

Back cover

Cover

DOI: 10.1039/C7PY90057K

You might also like

Compound Q&A

What precautions should be taken when handling lithium chloride hydrate (1:1:1) (CAS: 16712-20-2)?

When handling lithium chloride hydrate (1:1:1) (CAS: 16712-20-2), it is importan...

16712-20-2Lithium chloride hyd...
Compound Q&A

Is 4-(4H-1,2,4-Triazol-4-yl)piperidine (CAS: 690261-92-8) safe?

4-(4H-1,2,4-Triazol-4-yl)piperidine is generally considered safe for use in phar...

690261-92-84-(4H-1,2,4-Triazol-...
Compound Q&A

How should waste containing 1,3-Thiazole-2-carboxamide (CAS: 16733-85-0) be handled?

Waste containing 1,3-Thiazole-2-carboxamide (CAS: 16733-85-0) should be collecte...

16733-85-01,3-Thiazole-2-carbo...
Compound Q&A

What regulatory guidelines apply to 5-(Difluoromethyl)-2-fluorobenzonitrile (CAS: 934175-58-3)?

5-(Difluoromethyl)-2-fluorobenzonitrile (CAS: 934175-58-3) is subject to regulat...

934175-58-35-(Difluoromethyl)-2...
Compound Q&A

How is Methyl 3-acetamido-2-thiophenecarboxylate (CAS: 22288-79-5) typically synthesized?

Methyl 3-acetamido-2-thiophenecarboxylate can be synthesized by the reaction of ...

22288-79-5Methyl 3-acetamido-2...
Compound Q&A

What is 4-Isoquinolinecarbonitrile (CAS: 34846-65-6)?

4-Isoquinolinecarbonitrile is a chemical compound with the CAS number 34846-65-6...

34846-65-64-Isoquinolinecarbon...
Compound Q&A

How should Methyl 1H-1,2,3-triazole-4-carboxylate (CAS: 877309-59-6) be stored?

Store Methyl 1H-1,2,3-triazole-4-carboxylate (CAS: 877309-59-6) in a cool, dry p...

877309-59-6Methyl 1H-1,2,3-tria...
Compound Q&A

What regulatory guidelines apply to 6-Bromo[1,3]thiazolo[5,4-b]pyridin-2-amine (CAS: 1160791-13-8)?

6-Bromo[1,3]thiazolo[5,4-b]pyridin-2-amine (CAS: 1160791-13-8) is subject to the...

1160791-13-86-Bromo[1,3]thiazolo...
Compound Q&A

Is (2S,3S)-2-Ammonio-3-(3,4-dihydroxyphenyl)-3-hydroxypropanoate (CAS: 23651-95-8) safe?

(2S,3S)-2-Ammonio-3-(3,4-dihydroxyphenyl)-3-hydroxypropanoate (CAS: 23651-95-8) ...

23651-95-8(2S,3S)-2-Ammonio-3-...
Compound Q&A

What are the physical and chemical properties of 7-bromo-3-methyl-3,4-dihydroquinazolin-4-one (CAS: 1293987-84-4)?

7-Bromo-3-methyl-3,4-dihydroquinazolin-4-one is a solid with a crystalline form....

1293987-84-47-bromo-3-methyl-3,4...

Source Journal

Chemical Communications

Chemical Communications
CiteScore: 8.6
Self-citation Rate: 4.7%
Articles per Year: 2458

ChemComm publishes urgent research which is of outstanding significance and interest to experts in the field, while also appealing to the journal’s broad chemistry readership. Our communication format is ideally suited to short, urgent studies that are of such importance that they require accelerated publication. Our scope covers all topics in chemistry, and research at the interface of chemistry and other disciplines (such as materials science, nanoscience, physics, engineering and biology) where there is a significant novelty in the chemistry aspects. Major topic areas covered include: Analytical Chemistry Catalysis Chemical Biology and medicinal chemistry Computational Chemistry and Machine Learning Energy and sustainable chemistry Environmental Chemistry Green Chemistry Inorganic Chemistry Materials Chemistry Nanoscience Organic Chemistry Physical Chemistry Polymer Chemistry Supramolecular Chemistry

Recommended Suppliers

Disclaimer
This page provides academic journal information for reference and research purposes only. We are not affiliated with any journal publishers and do not handle publication submissions. For publication-related inquiries, please contact the respective journal publishers directly.
If you notice any inaccuracies in the information displayed, please contact us at support@chemtradehub.com. We will promptly review and address your concerns.