Copper-catalyzed enantioselectivecarbenoidinsertion into S–H bonds‡
Literature Information
Yong-Zhen Zhang, Shou-Fei Zhu, Yan Cai, Hong-Xiang Mao, Qi-Lin Zhou
An asymmetriccarbenoidinsertion into S–H bonds catalyzed by copper–chiral spiro bisoxazoline complexes has been developed, in which a series of α-mercaptoesters were produced in high yields with moderate to good enantioselectivities (up to 85% ee); this result represents the best enantioselectivity in the catalytic asymmetriccarbenoid S–H bond insertion reaction.
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