Intercepting the synthesis of triazine dendrimers with nucleophilic pharmacophores: a general strategy toward drug delivery vehicles
Literature Information
Publication Date
2009-08-11
DOI
10.1039/B911353C
Impact Factor
6.222
Authors
Vincent J. Venditto, Kimberly Allred, Clinton D. Allred, Eric E. Simanek
View Original
Abstract
The camptothecin ester of isonipecotic acid is installed on a triazine dendrimer intermediate obtained through an iterative, scalable route to ultimately yield cationic and PEGylated targets with activities in cell culture comparable to free drug.
Related Literature
An efficient entry to 1,2-benzisoxazoles via1,3-dipolar cycloaddition of in situ generated nitrile oxides and benzyne
Christopher Mason, Fengzhi Zhang, Dougal J. Ritson, Steve Keeling, John E. Moses
2010-04-07
Paper
DOI: 10.1039/B927235F
Highly selective fluorescent probe for Au3+ based on cyclization of propargylamide
Min Jung Jou, Xiaoqiang Chen, Ha Na Kim, Hae-Jo Kim, Sang-gi Lee
2009-10-22
Communication
DOI: 10.1039/B917832E
Salt, pH and thermoresponsive supramolecular hydrogel of N-(4-n-tetradecyloxybenzoyl)-l-carnosine
Amrita Pal, Saurabh Shrivastava, Joykrishna Dey
2009-10-06
Communication
DOI: 10.1039/B914665B
Porous graphenes: two-dimensional polymer synthesis with atomic precision
Marco Bieri, Matthias Treier, Jinming Cai, Kamel Aït-Mansour, Pascal Ruffieux, Oliver Gröning, Pierangelo Gröning, Marcel Kastler, Ralph Rieger, Xinliang Feng, Klaus Müllen
2009-09-11
Communication
DOI: 10.1039/B915190G
Stereoselective synthesis of enynones via base-catalyzed isomerization of 1,5-disubstituted-2,4-pentadiynyl silyl ethers or their alcohol derivatives
Jingjin Chen, Guoqin Fan, Yuanhong Liu
2010-09-16
Communication
DOI: 10.1039/C0OB00344A
Synthesis of new pentacyclic chromophores through a highly regio- and diastereoselective cascade process‡
Zein el abidine Chamas, Emmanuel Aubert, Yves Fort, Victor Mamane
2010-09-16
Communication
DOI: 10.1039/C0OB00390E
A triple-stranded helicate and mesocate from the same metal and ligand
Zhan Zhang, David Dolphin
2009-10-21
Communication
DOI: 10.1039/B913231G
A nanophase segregated mesophase morphology in self-organized novel disc–rod oligomesogens
Hari Krishna Bisoyi, V. A. Raghunathan, Sandeep Kumar
2009-10-14
Communication
DOI: 10.1039/B911383E
Synthesis of 3-amino-thiochromanes from 4-benzyl 2-thiazolines, via an unprecedented intramolecular electrophilic aromatic substitution
Guillaume Mercey, Remi Legay, Jean-François Lohier, Jana Sopkova-de Oliveira Santos, Jocelyne Levillain, Annie-Claude Gaumont, Mihaela Gulea
2010-04-22
Communication
DOI: 10.1039/C003050C
Asymmetric epoxidation of 2-arylidene-1,3-diketones: facile access to synthetically useful epoxides
Alessio Russo, Alessandra Lattanzi
2010-04-01
Paper
DOI: 10.1039/C002587A
You might also like
Compound Q&A
What industries use (1R,3S)-1,3-Cyclopentanediol (CAS: 16326-97-9)?
(1R,3S)-1,3-Cyclopentanediol finds applications in various industries. In the ph...
16326-97-9(1R,3S)-1,3-Cyclopen...
Compound Q&A
What precautions should be taken when handling N'-[4-(Dimethylamino)phenyl]-N,N-dimethyl-1,4-benzenediamine (CAS: 637-31-0)?
When handling N'-[4-(Dimethylamino)phenyl]-N,N-dimethyl-1,4-benzenediamine, it i...
637-31-0N'-[4-(Dimethylamino...
Compound Q&A
Are there alternatives to 5-(2,4-Difluorophenyl)-2-methoxypyrimidine (CAS: 1352318-16-1) in synthesis?
There are several alternatives to 5-(2,4-Difluorophenyl)-2-methoxypyrimidine in ...
1352318-16-15-(2,4-Difluoropheny...
Compound Q&A
What regulatory guidelines apply to 1-(3-Methoxyphenoxy)propan-2-ol (CAS: 382141-68-6)?
1-(3-Methoxyphenoxy)propan-2-ol (CAS: 382141-68-6) must comply with the Globally...
382141-68-61-(3-Methoxyphenoxy)...
Compound Q&A
Is Tetrodotoxin Citrate (CAS: 18660-81-6) safe?
Tetrodotoxin Citrate is extremely dangerous and should be handled with extreme c...
18660-81-6Tetrodotoxin Citrate
Compound Q&A
What are the main uses of 2-Methyl-2-propanyl [(1R,3S)-3-hydroxycyclopentyl]carbamate (CAS: 225641-84-9)?
2-Methyl-2-propanyl [(1R,3S)-3-hydroxycyclopentyl]carbamate (CAS: 225641-84-9) i...
225641-84-92-Methyl-2-propanyl ...
Compound Q&A
How should waste containing 4-(2-Hydroxyhexafluoroisopropyl)Benzoic Acid (CAS: 16261-80-6) be handled?
Waste containing 4-(2-Hydroxyhexafluoroisopropyl)Benzoic Acid (CAS: 16261-80-6) ...
16261-80-64-(2-Hydroxyhexafluo...
Compound Q&A
How is 2-Methyl-2-proanyl {(2S)-1-[(benzyloxy)amino]-3-hydroxy-3-methyl-1-oxo-2-butanyl}carbamate (CAS: 102507-19-7) typically synthesized?
2-Methyl-2-proanyl {(2S)-1-[(benzyloxy)amino]-3-hydroxy-3-methyl-1-oxo-2-butanyl...
102507-19-72-Methyl-2-propanyl ...
Compound Q&A
What is Benzeneethanamine, α-ethyl-, hydrochloride (1:1) (CAS: 20735-15-3)?
Benzeneethanamine, α-ethyl-, hydrochloride (1:1) is an organic compound with the...
20735-15-3Benzeneethanamine, α...
Compound Q&A
Are there alternatives to 3-{(E)-[4-(Dimethylamino)phenyl]diazenyl}benzoic acid (CAS: 20691-84-3) in synthesis?
In the synthesis of compounds similar to 3-{(E)-[4-(Dimethylamino)phenyl]diazeny...
20691-84-33-{(E)-[4-(Dimethyla...
Source Journal
Chemical Communications
CiteScore:
8.6
Self-citation Rate:
4.7%
Articles per Year:
2458
ChemComm publishes urgent research which is of outstanding significance and interest to experts in the field, while also appealing to the journal’s broad chemistry readership. Our communication format is ideally suited to short, urgent studies that are of such importance that they require accelerated publication. Our scope covers all topics in chemistry, and research at the interface of chemistry and other disciplines (such as materials science, nanoscience, physics, engineering and biology) where there is a significant novelty in the chemistry aspects. Major topic areas covered include: Analytical Chemistry Catalysis Chemical Biology and medicinal chemistry Computational Chemistry and Machine Learning Energy and sustainable chemistry Environmental Chemistry Green Chemistry Inorganic Chemistry Materials Chemistry Nanoscience Organic Chemistry Physical Chemistry Polymer Chemistry Supramolecular Chemistry
Recommended Compounds
N,N-Dimethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyrimidinamine
CAS Number:
1032759-30-0
Molecular Formula:
C12H20BN3O2
Recommended Suppliers
Disclaimer
This page provides academic journal information for reference and research purposes only. We are not affiliated with any journal publishers and do not handle publication submissions. For publication-related inquiries, please contact the respective journal publishers directly.
If you notice any inaccuracies in the information displayed, please contact us at support@chemtradehub.com. We will promptly review and address your concerns.