The effect of DNA aptamer configuration on the sensitivity of detection thrombin at surface by acoustic method

Literature Information

Publication Date 2009-09-08
DOI 10.1039/B910981A
Impact Factor 6.222
Authors

Tibor Hianik, Igor Grman, Ivana Karpisova


View Original

Abstract

Using an acoustic method we showed that the aptamer configuration, especially those comprised of dimers with binding exosites sensitive to heparin and fibrinogen at thrombin, substantially increases the aptasensor sensitivity.

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