Efficient synthesis of dendrimersvia a thiol–yne and esterification process and their potential application in the delivery of platinum anti-cancer drugs

Literature Information

Publication Date 2009-09-04
DOI 10.1039/B910340F
Impact Factor 6.222
Authors

Gaojian Chen, Jatin Kumar, Andrew Gregory, Martina H. Stenzel


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Abstract

A combination of thiol–yne chemistry and esterification reactions were successfully applied for the preparation of dendrimers with an array of terminal functionalities via the divergent growth strategy; maximizing the number of reactive chain ends whilst minimizing the number of reaction steps required in the process.

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