Synthesis of a monophosphoryl lipid A derivative and its conjugation to a modified form of a tumor-associated carbohydrateantigen GM3

Literature Information

Publication Date 2009-08-27
DOI 10.1039/B907351E
Impact Factor 6.222
Authors

Qianli Wang, Jie Xue, Zhongwu Guo


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Abstract

An efficient synthesis of a derivative of monophosphoryl lipid A suitable for coupling to various structures for the construction of glycoconjugate vaccines and its conjugation with an N-modified form of the tumor-associated antigen GM3 is presented.

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DOI: 10.1039/C7PY90085F

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DOI: 10.1039/C8PY90137F

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