Concise total synthesis of (±)-aspidospermidinevia an oxidative Hosomi–Sakurai process

Literature Information

Publication Date 2009-04-27
DOI 10.1039/B903530C
Impact Factor 6.222
Authors

Cyrille Sabot, Kimiaka C. Guérard, Sylvain Canesi


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Abstract

A concise total synthesis of (±)-aspidospermidine has been achieved in twelve steps from inexpensive 4-ethylphenol, based on an oxidative Hosomi–Sakurai reaction via the concept of “aromatic ring umpolung”.

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