Electrochemical assay of superoxide based on biomimetic enzyme at highly conductive TiO2 nanoneedles: from principle to applications in living cells

Literature Information

Publication Date 2009-04-07
DOI 10.1039/B902150G
Impact Factor 6.222
Authors

Yongping Luo, Yang Tian, Qi Rui


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Abstract

A novel strategy for extremely durable, reliable, and selective in situ real-time determination of superoxide anion (O2˙−) based on direct electron transfer of a biomimeticsuperoxide dismutase (SOD), Mn3(PO4)2, at highly conductive TiO2 nanoneedles is reported for the first time, and is further exploited for the determination of O2˙− from living normal and cancer ovary cells directly adhered onto the modified surface, suggesting that O2˙− might be proposed as a biomarker of cancer.

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