![Benzeneacetic acid, 2-bromo-α-[[(1,1-dimethylethoxy)carbonyl]amino]-, (αS)- structure](https://static.chemtradehub.com/structs/122/1228547-87-2-f296.webp "Benzeneacetic acid, 2-bromo-α-[[(1,1-dimethylethoxy)carbonyl]amino]-, (αS)- structure")
Benzeneacetic acid, 2-bromo-α-[[(1,1-dimethylethoxy)carbonyl]amino]-, (αS)-
CAS Number:
1228547-87-2
Molecular Formula:
C13H16BrNO4
Sensitive and selective detection ofcysteine using gold nanoparticles as colorimetric probes
Literature Information
Publication Date
2009-04-02
DOI
10.1039/B819842J
Impact Factor
4.616
Authors
Li Li, Baoxin Li
View Original
Abstract
We report herein the development of a highly sensitive and selective colorimetric detection method for cysteine using gold nanoparticles probes. This assay relies upon the distance-dependent optical properties of gold nanoparticles, the self-assembly of cysteine on gold nanoparticles, and the interaction of a 2:1 cysteine/Cu2+ complex. In the presence of Cu2+, cysteine could rapidly induce the aggregation of gold nanoparticles, thereby resulting in red-to-blue (or purple) color change. The concentration of cysteine can be determined by monitoring with the naked eye or a UV-vis spectrometer. The present limit of detection for cysteine is 10 nM. This method exhibits excellent selectivity for cysteine over other α-amino acids, glutathione, thioglycolic acid and mercaptoethyl alcohol.
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Source Journal
Analyst
CiteScore:
7.8
Self-citation Rate:
5.6%
Articles per Year:
653
Analyst publishes analytical and bioanalytical research that reports premier fundamental discoveries and inventions, and the applications of those discoveries, unconfined by traditional discipline barriers.
Recommended Compounds
![Ethyl 4-[8-chloro(5,5,6,6,7-~2~H_5_)-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene]-1-piperidinecarboxylate structure](https://static.chemtradehub.com/structs/102/1020719-57-6-37e2.webp "Ethyl 4-[8-chloro(5,5,6,6,7-~2~H_5_)-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene]-1-piperidinecarboxylate structure")
Ethyl 4-[8-chloro(5,5,6,6,7-~2~H_5_)-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene]-1-piperidinecarboxylate
CAS Number:
1020719-57-6
Molecular Formula:
C22H18D5ClN2O2
4-(Bromomethyl)-1-cyclohexyl-2-(trifluoromethyl)benzene
CAS Number:
800381-60-6
Molecular Formula:
C14H16BrF3
4-Methyl-2-oxo-2H-chromen-7-yl 2-acetamido-2-deoxy-3-O-(6-deoxy-alpha-L-galactopyranosyl)-beta-D-glucopyranoside
CAS Number:
383160-12-1
Molecular Formula:
C24H31NO12
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