Bisbenzimidazole to benzobisimidazole: from binding B-form duplex DNA to recognizing different modes of telomereG-quadruplex
Literature Information
Jing Huang, Guorui Li, Zhiguo Wu, Zhibin Song, Yangyang Zhou, Liang Shuai, Xiaocheng Weng, Xiang Zhou, Guangfu Yang
A bisbenzimidazole was discovered to bind helix DNA, while related benzobisimidazole derivatives were found to bind and induce different G-quadruplex isomers.
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Chemical Communications

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![4-Fluoro-2-(4-{[(3S,4R)-4-(2-hydroxy-2-propanyl)-3-pyrrolidinyl]amino}-6,7-dimethoxy-2-quinazolinyl)phenol hydrochloride (1:1) structure 4-Fluoro-2-(4-{[(3S,4R)-4-(2-hydroxy-2-propanyl)-3-pyrrolidinyl]amino}-6,7-dimethoxy-2-quinazolinyl)phenol hydrochloride (1:1) structure](https://static.chemtradehub.com/structs/143/1431697-96-9-619c.webp)


