Molecularly imprinted cavities template the macrocyclization of tetrapeptides

Literature Information

Publication Date 2008-09-29
DOI 10.1039/B813439A
Impact Factor 6.222
Authors

Dar-Fu Tai, Yee-Fung Lin


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Abstract

Cavities formed using cyclic tetrapeptides (CTPs) or heat-induced conformers act as templates for cyclization; the cavities bind to linear tetrapeptides and enforce turn conformations to enhance cyclization to constrained CTPs.

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