Binding enhancement of antigen-functionalized PEGylated gold nanoparticles onto antibody-immobilized surface by increasing the functionalized antigen using α-sulfanyl-ω-amino-PEG

Literature Information

Publication Date 2008-09-16
DOI 10.1039/B811818C
Impact Factor 6.222
Authors

Yuki Hoshino, Takehiko Ishii


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Abstract

We established a technique for constructing PEGylated gold nanoparticles (GNP) that have small compounds with almost complete functionalities on their surfaces using a newly synthesized hetero-telechelic poly(ethylene glycol) (PEG), and their association/dissociation behavior on an antibody-immobilized surface was evaluated using a surface plasmon resonance (SPR) sensor.

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