Dynamic resolution of N-Boc-2-lithiopiperidine

Literature Information

Publication Date 2008-08-08
DOI 10.1039/B810988E
Impact Factor 6.222
Authors

Iain Coldham, Sophie Raimbault, Praful T. Chovatia, Jignesh J. Patel, Daniele Leonori, Nadeem S. Sheikh, David T. E. Whittaker


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Abstract

Dynamic thermodynamic resolution of N-Boc-2-lithiopiperidine is possible using a chiral ligand; the two enantiomers of this organolithium can be resolved with selectivities of up to 85 : 15 from a selection of 26 chiral diamino-alkoxide ligands screened.

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Back cover

2023-12-11 Cover

DOI: 10.1039/D3NJ90188B

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