Dynamic resolution of N-Boc-2-lithiopiperidine
Literature Information
Iain Coldham, Sophie Raimbault, Praful T. Chovatia, Jignesh J. Patel, Daniele Leonori, Nadeem S. Sheikh, David T. E. Whittaker
Dynamic thermodynamic resolution of N-Boc-2-lithiopiperidine is possible using a chiral ligand; the two enantiomers of this organolithium can be resolved with selectivities of up to 85 : 15 from a selection of 26 chiral diamino-alkoxide ligands screened.
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