Subtractive assembly of DNA nanoarchitectures driven by fuel strand displacement

Literature Information

Publication Date 2008-07-17
DOI 10.1039/B807933A
Impact Factor 6.222
Authors

Zhe Li, Yonggang Ke, Chenxiang Lin, Hao Yan, Yan Liu


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Abstract

Herein we demonstrate that flexible DNA architectures with larger cavities can be efficiently constructed by first assembling a relatively more rigid DNA tile architecture and subsequently subtracting a center tile through fuel strand displacement; such structures are otherwise difficult to obtain if the center tile is missing in the beginning, proving a new strategy for DNA self-assembly.

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