Subtractive assembly of DNA nanoarchitectures driven by fuel strand displacement
Literature Information
Zhe Li, Yonggang Ke, Chenxiang Lin, Hao Yan, Yan Liu
Herein we demonstrate that flexible DNA architectures with larger cavities can be efficiently constructed by first assembling a relatively more rigid DNA tile architecture and subsequently subtracting a center tile through fuel strand displacement; such structures are otherwise difficult to obtain if the center tile is missing in the beginning, proving a new strategy for DNA self-assembly.
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