Can the night-time atmospheric oxidantNO3˙ damage aromatic amino acids?

Literature Information

Publication Date 2008-04-02
DOI 10.1039/B803456G
Impact Factor 6.222
Authors

Duanne C. E. Sigmund, Uta Wille


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Abstract

Reaction of nitrate radicals, NO3˙, with aromatic amino acids leads to irreversible oxidative functionalization at the β-position or at the aromatic ring, suggesting that this important atmospheric oxidant could potentially cause damage to peptides lining the respiratory tract and may contribute to pollution-derived diseases.

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