Catalytic aerobic oxidation of substituted 8-methylquinolines in PdII-2,6-pyridinedicarboxylic acid systems
Literature Information
Jing Zhang, Eugene Khaskin, Nicholas P. Anderson, Peter Y. Zavalij, Andrei N. Vedernikov
The ability of PdII complexes derived from 2,6-pyridinedicarboxylic acids to catalyze homogeneous regioselective aerobic oxidation of 5- and 6-substituted 8-methylquinolines in AcOH–Ac2O solution to produce corresponding 8-quinolylmethyl acetates in high yield was demonstrated; corresponding 8-quinoline carboxylic acids are minor reaction products.
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