![10-(1-Azabicyclo[2.2.2]oct-3-ylmethyl)-10H-phenothiazine structure](https://static.chemtradehub.com/structs/292/29216-28-2-1d81.webp "10-(1-Azabicyclo[2.2.2]oct-3-ylmethyl)-10H-phenothiazine structure")
10-(1-Azabicyclo[2.2.2]oct-3-ylmethyl)-10H-phenothiazine
CAS Number:
29216-28-2
Molecular Formula:
C20H22N2S
A facile in situ generation of dithiocarbamate ligands for stable gold nanoparticle–oligonucleotide conjugates
Literature Information
Publication Date
2008-02-29
DOI
10.1039/B800109J
Impact Factor
6.222
Authors
Jaswinder Sharma, Rahul Chhabra, Hao Yan, Yan Liu
View Original
Abstract
Here we demonstrate a facile strategy of preparing gold nanoparticle (AuNP) and DNA conjugates by in situ generation of strong metal affinity capping ligands, dithiocarbamates (DTC) modified oligonucleotides; the conjugates produced are stable at elevated temperature, resistant to ligand displacement and preserve the functionality of the conjugated oligonucleotides.
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Source Journal
Chemical Communications
CiteScore:
8.6
Self-citation Rate:
4.7%
Articles per Year:
2458
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