Crystal structure and silica condensing activities of silicatein α–cathepsin L chimeras‡
Literature Information
Michael Fairhead, Kenneth A. Johnson, Thomas Kowatz, Stephen A. McMahon, Lester G. Carter, Muse Oke, Huanting Liu, James H. Naismith, Christopher F. van der Walle
Cathepsin L mutants with the ability to condense silica from solution have been generated and a 1.5 Å crystal structure of one of these chimeras allows us to rationalise the catalytic mechanism of silicic acid condensation.
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