Metal-specific allosteric activation and deactivation of a diamine
Literature Information
Hayley J. Clayton, Lindsay P. Harding, John P. Irvine, John C. Jeffery, T. Riis-Johannessen, Andrew P. Laws, Craig R. Rice, Martina Whitehead
The reaction of a potentially tetradentate bis(pyridyl–thiazole) ligand with acetone is allosterically activated upon complexation with Cd(II) but deactivated by reaction with Cu(I), demonstrating metal-specific allosteric controlled reactivity.
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![(4aR,5S,6R,8aS)-5-[2-(3-Furyl)ethyl]-8a-(hydroxymethyl)-5,6-dimethyl-3,4,4a,5,6,7,8,8a-octahydro-1-naphthalenecarboxylic acid structure (4aR,5S,6R,8aS)-5-[2-(3-Furyl)ethyl]-8a-(hydroxymethyl)-5,6-dimethyl-3,4,4a,5,6,7,8,8a-octahydro-1-naphthalenecarboxylic acid structure](https://static.chemtradehub.com/structs/184/18411-75-1-d4cd.webp)

