Solid-phase based synthesis of jasplakinolide analogs by intramolecular azide–alkyne cycloadditions

Literature Information

Publication Date 2007-08-14
DOI 10.1039/B710650E
Impact Factor 6.222
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Abstract

The synthesis of a focused library of jasplakinolide analogs with a 1,2,3-triazole in place of an E-configured double bond is described, featuring the Cu(I) catalyzed azide–alkyne cycloaddition reaction as an efficient macrocyclization tool.

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