Chimeric peptide beacons: a direct polypeptide analog of DNA molecular beacons

Literature Information

Publication Date 2007-10-26
DOI 10.1039/B709776J
Impact Factor 6.222
Authors

Kenneth J. Oh, Kevin J. Cash, Arica A. Lubin


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Abstract

We have developed a new biosensor architecture, which is comprised of a polypeptide–peptide nucleic acid tri-block co-polymer and which we have termed chimeric peptide beacons (CPB), that generates an optical output via a mechanism analogous to that employed in DNA-based molecular beacons.

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