(S)-3-((tert-Butoxycarbonyl)amino)-4-(4-(tert-butyl)phenyl)butanoic acid
CAS Number:
403661-85-8
Molecular Formula:
C19H29NO4
Chromogenic and fluorogenic reagents for chemical warfare nerve agents' detection
Literature Information
Publication Date
2007-08-23
DOI
10.1039/B707063B
Impact Factor
6.222
Authors
Santiago Royo, Ramón Martínez-Máñez, Félix Sancenón, Ana M. Costero, Margarita Parra, Salvador Gil
View Original
Abstract
The ease of production, the extreme toxicity of organophosphorus-containing nerve agents, and their facile use in terrorism attacks underscores the need to develop accurate systems to detect these chemicals. Among different technologies we review here recent advances in the design of chromo-fluorogenic methods for the specific detection of nerve agents. Optical sensing (especially colorimetric detection) requires usually low-cost and widely used instrumentation and offers the possibility of so-called “naked eye detection”. Recent reported examples suggest that the application of chromo-fluorogenic supramolecular concepts for the chromogenic or fluorogenic sensing of nerve agents might be an area of increasing interest that would allow developing systems able to overcome some of the limitations shown by classical analytical methods.
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Source Journal
Chemical Communications
CiteScore:
8.6
Self-citation Rate:
4.7%
Articles per Year:
2458
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