Adenosine residues in the template do not block spontaneous replication steps of RNA

Literature Information

Publication Date 2007-04-12
DOI 10.1039/B702768K
Impact Factor 6.222
Authors

Stephanie R. Vogel, Clemens Richert


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Abstract

Sub-freezing temperatures, azabenzotriazolide activation, multiple monomer addition, and helper displacement help to overcome what seemed like an intrinsic block of adenine-templated RNA replication steps in the absence of enzymes.

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