Synthesis of two diastereomeric C1–C22 fragments of spirastrellolide A
Literature Information
Ian Paterson, Edward A. Anderson, Stephen M. Dalby, Julien Genovino, Jong Ho Lim, Christian Moessner
The optimisation of a synthetic strategy towards the ABC segment of the cytotoxic macrolide spirastrellolide A is reported, together with its application to the synthesis of two diastereomeric C1–C22 fragments for stereochemical correlation purposes with a putative spirastrellolide degradation product.
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