Quantitative detection of protein expression in single cells using droplet microfluidics
Literature Information
M. Srisa-Art, F. Hollfelder, A. J. deMello
We demonstrate that single cells can be controllably compartmentalized within aqueous microdroplets; using such an approach we perform high-throughput screening by detecting the expression of a fluorescent protein in individual cells with simultaneous measurement of droplet size and cell occupancy.
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