Robust monolithic silica-based on-chip electro-osmotic micro-pump
Literature Information
Fu-Qiang Nie, Mirek Macka, Leon Barron, Damian Connolly, Nigel Kent, Brett Paull
A robust, compact, on-chip, electro-osmotic micro-pump (EOP) for micro-flow analysis, based on parallel, encased, 10 × 0.1 mm I.D. monolithic silica capillary columns has been developed. A 15 × 40 × 2 mm poly(methyl methacrylate) (PMMA) chip, containing a total of nine parallel EOP systems was fabricated, allowing the use of single, double or triple monolithic columns to produce increased flow as required. The monolithic silica was compatible with both aqueous and organic solvents without swelling or shrinking problems, with the triple column EOP capable of generating flow of up to 0.6 μL min−1 under zero pressure load and over 0.1 μL min−1 with an applied pressure of ca. 2.4 bar using an applied voltage of just 2 kV. Current generated at the 2 kV applied voltage for a 2 mM acetate buffer solution (pH 4.5) was under 4 μA, allowing stable, bubble-free flow. The developed triple column EOP was incorporated within a micro-fluidic chip (5.0 × 2.0 × 0.4 cm) integrated with a second single 10 × 0.1 mm column EOP, for combined sample injection and simple on-chip micro-flow analysis.
Related Literature
Atomistic modeling of La3+ doping segregation effect on nanocrystalline yttria-stabilized zirconia
Shenli Zhang, Haoyan Sha, Ricardo H. R. Castro, Roland Faller
DOI: 10.1039/C8CP02010H
Open flow non-enzymatic template catalysis and replication
Larwsk H. Gonçalves da Silva, David Hochberg
DOI: 10.1039/C8CP01828F
Virtually imprinted polymers (VIPs): understanding molecularly templated materials via molecular dynamics simulations
F. A. Moura, P. Alves da Silva Autreto, D. S. Galvão
DOI: 10.1039/C7CP08284C
Effects of 1-hexanol on C12E10 micelles: a molecular simulations and light scattering study
Sampsa Vierros, Maria Sammalkorpi
DOI: 10.1039/C7CP07511A
Phenothiazine-based small-molecule organic solar cells with power conversion efficiency over 7% and open circuit voltage of about 1.0 V using solvent vapor annealing
Yogajivan Rout, Rajneesh Misra, Rahul Singhal, Subhayan Biswas, Ganesh D. Sharma
DOI: 10.1039/C7CP08308D
Newly synthesized quercetin derivatives as corrosion inhibitors for mild steel in 1 M HCl: combined experimental and theoretical investigation
Dipankar Sukul, Aparesh Pal, Sanjoy Satpati, Utpal Adhikari
DOI: 10.1039/C7CP06848D
Use multiscale simulation to explore the effects of the homodimerizations between different conformation states on the activation and allosteric pathway for the μ-opioid receptor
Xi Zhang, Yuan Yuan, Longrong Wang, Yanzhi Guo, Menglong Li, Chuan Li, Xuemei Pu
DOI: 10.1039/C8CP02016G
Ammonolysis of ketene as a potential source of acetamide in the troposphere: a quantum chemical investigation
Saptarshi Sarkar, Subhasish Mallick, Pradeep Kumar, Biman Bandyopadhyay
DOI: 10.1039/C8CP01650J
Spatiotemporal dynamics of minimal bromate oscillators in an open one-side-fed reactor
Krisztina Kurin-Csörgei, István Szalai
DOI: 10.1039/C8CP01953C
You might also like
What precautions should be taken when handling 2-Chloro-1,2-bis(4-methylphenyl)ethanone (CAS: 71193-32-3)?
When handling 2-Chloro-1,2-bis(4-methylphenyl)ethanone (CAS: 71193-32-3), it is ...
What industries use 4-Ethoxy-3-(5-methyl-4-oxo-7-propyl-1,4-dihydroimidazo[5,1-f][1,2,4]triazin-2-yl)benzenesulfonyl chloride (CAS: 224789-26-8)?
4-Ethoxy-3-(5-methyl-4-oxo-7-propyl-1,4-dihydroimidazo[5,1-f][1,2,4]triazin-2-yl...
How should Methyl 3-Oxo-4-Androsten-17-Carboxylate (CAS: 2681-55-2) be stored?
Methyl 3-Oxo-4-Androsten-17-Carboxylate (CAS: 2681-55-2) should be stored in a c...
What are the main uses of (R)-3-Amino-4-(3-hexylphenylamino)-4-oxobutylphosphonic acid (CAS: 909725-61-7)?
(R)-3-Amino-4-(3-hexylphenylamino)-4-oxobutylphosphonic acid is primarily used i...
What regulatory guidelines apply to 2-Methyl-2-propanyl 3-amino-3-carbamoyl-1-azetidinecarboxylate (CAS: 1254120-14-3)?
2-Methyl-2-propanyl 3-amino-3-carbamoyl-1-azetidinecarboxylate (CAS: 1254120-14-...
Are there alternatives to (E)-4-(tert-Butoxy)-4-oxobut-2-enoic acid (CAS: 135355-96-3) in synthesis?
There are alternative reagents that can be used in synthesis instead of (E)-4-(t...
What are the physical and chemical properties of [2-(3-Chlorophenyl)-1,3-thiazol-4-yl]methanol (CAS: 121202-20-8)?
[2-(3-Chlorophenyl)-1,3-thiazol-4-yl]methanol (CAS: 121202-20-8) is a crystallin...
What is the market or research trend for Methyl (2S)-[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]{[(4-methylphenyl)sulfonyl]oxy}acetate (CAS: 166249-17-8)?
The market and research trends for Methyl (2S)-[(4S)-2,2-dimethyl-1,3-dioxolan-4...
What is the market or research trend for 1-Bromo-2-isocyanatoethane (CAS: 42865-19-0)?
The market for 1-Bromo-2-isocyanatoethane (CAS: 42865-19-0) is driven by its use...
What are the main uses of 4-Nitro-D-phenylalanine hydrochloride (CAS: 147065-06-3)?
4-Nitro-D-phenylalanine hydrochloride (CAS: 147065-06-3) is primarily used in re...
Source Journal
Analyst

Analyst publishes analytical and bioanalytical research that reports premier fundamental discoveries and inventions, and the applications of those discoveries, unconfined by traditional discipline barriers.













![2-Hydroxy-4-[({[(4-methylphenyl)sulfonyl]oxy}acetyl)amino]benzoic acid structure 2-Hydroxy-4-[({[(4-methylphenyl)sulfonyl]oxy}acetyl)amino]benzoic acid structure](https://static.chemtradehub.com/structs/501/501919-59-1-579f.webp)
